Ethyl 3-[(2-thienylmethyl)amino]propanoate

Base Information

Chemical Name:Ethyl 3-[(2-thienylmethyl)amino]propanoate
CAS No.:131436-68-5
Molecular Formula:C₁₀H₁₅NO₂S
Molecular Weight:213.301
Hs Code.:
DSSTox Substance ID:DTXSID601269932
Mol file:131436-68-5.mol

Synonyms:131436-68-5;ETHYL 3-[(2-THIENYLMETHYL)AMINO]PROPANOATE;ethyl 3-{[(thiophen-2-yl)methyl]amino}propanoate;ethyl N-(thien-2-ylmethyl)-beta-alaninate;ethyl 3-[(thiophen-2-ylmethyl)amino]propanoate;ethyl 3-(thiophen-2-ylmethylamino)propanoate;Ethyl 3-((thiophen-2-ylmethyl)amino)propanoate;SCHEMBL2837713;RVUKMQHTMQHBPR-UHFFFAOYSA-N;DTXSID601269932;MFCD03450395;AKOS004911005;Ethyl 3-[(thiophen-2-ylmethyl)amino]propionate

Suppliers and Price of Ethyl 3-[(2-thienylmethyl)amino]propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 3-[(2-thienylmethyl)amino]propanoate
500mg
$ 199.00

American Custom Chemicals Corporation
ETHYL-3-[(2-THIENYLMETHYL)AMINO]PROPANOATE 95.00%
500MG
$ 795.80

Total 3 raw suppliers

Chemical Property of Ethyl 3-[(2-thienylmethyl)amino]propanoate

Chemical Property:

Boiling Point:118-126 °C(Press: 3.0 Torr)
PKA:8.02±0.19(Predicted)
Density:1.122±0.06 g/cm3(Predicted)
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:213.08234989
Heavy Atom Count:14
Complexity:176

Purity/Quality:

99% ^*data from raw suppliers

Ethyl 3-[(2-thienylmethyl)amino]propanoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CCNCC1=CC=CS1

Technology Process of Ethyl 3-[(2-thienylmethyl)amino]propanoate

There total 5 articles about Ethyl 3-[(2-thienylmethyl)amino]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 27757-85-3
2-Aminomethylthiophene

: 1617-18-1
ethyl 3-butenoate

: 131436-68-5
ethyl 3-<(2-thienylmethyl)amino>propionate

Guidance literature:: In ethanol;
DOI:10.1021/jm00107a020

Reference yield:

: 98-03-3
thiophene-2-carbaldehyde

: 4244-84-2
ethyl β-alaninate hydrochloride

: 131436-68-5
ethyl 3-<(2-thienylmethyl)amino>propionate

Guidance literature:: thiophene-2-carbaldehyde; ethyl β-alaninate hydrochloride; With triethylamine; In methanol; at 20 ℃;

With methanol; sodium tetrahydroborate; at 0 - 20 ℃;

Reference yield:

: 27757-85-3
2-Aminomethylthiophene

: 539-74-2
Ethyl 3-bromopropionate

: 131436-68-5
ethyl 3-<(2-thienylmethyl)amino>propionate

Guidance literature:: 2-Aminomethylthiophene; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 25 ℃; for 0.5h;

Ethyl 3-bromopropionate; In N,N-dimethyl-formamide; at 25 ℃; for 16h;
DOI:10.1016/j.ejmech.2018.09.065