(2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-1-{[2-(4-methoxyphenyl)ethyl]-1,3-dithian-2-yl}heptadecan-2-ol

Base Information

• Chemical Name: (2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-1-{[2-(4-methoxyphenyl)ethyl]-1,3-dithian-2-yl}heptadecan-2-ol
• CAS No.: 1235479-26-1
• Molecular Formula: C₃₆H₆₆O₃S₂Si
• Molecular Weight: 639.136
• Mol file: 1235479-26-1.mol

Synonyms:(2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-1-{[2-(4-methoxyphenyl)ethyl]-1,3-dithian-2-yl}heptadecan-2-ol

Chemical Property of (2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-1-{[2-(4-methoxyphenyl)ethyl]-1,3-dithian-2-yl}heptadecan-2-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-1-{[2-(4-methoxyphenyl)ethyl]-1,3-dithian-2-yl}heptadecan-2-ol

There total 1 articles about (2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-1-{[2-(4-methoxyphenyl)ethyl]-1,3-dithian-2-yl}heptadecan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(2R)-2-[(tert-butyldimethylsilyl)oxy]-1-[(2R)-oxiran-2-yl]pentadecane (1202063-96-4) + 2-[2-(4-methoxyphenyl)ethyl]-1,3-dithiane (56438-60-9) → (2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-1-{[2-(4-methoxyphenyl)ethyl]-1,3-dithian-2-yl}heptadecan-2-ol (1235479-26-1)

Guidance literature:

2-[2-(4-methoxyphenyl)ethyl]-1,3-dithiane; With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; Inert atmosphere;

(2R)-2-[(tert-butyldimethylsilyl)oxy]-1-[(2R)-oxiran-2-yl]pentadecane; In tetrahydrofuran; hexane; Inert atmosphere;

DOI:10.1055/S-0029-1218687

Reference yield:

(2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-1-{[2-(4-methoxyphenyl)ethyl]-1,3-dithian-2-yl}heptadecan-2-ol (1235479-26-1) → C29H50O3S2 (1187560-44-6)

Guidance literature:

With boron tribromide; In dichloromethane; at -78 - 25 ℃; Inert atmosphere;

DOI:10.1055/S-0029-1218687

upstream raw materials:

(2R)-2-[(tert-butyldimethylsilyl)oxy]-1-[(2R)-oxiran-2-yl]pentadecane

2-[2-(4-methoxyphenyl)ethyl]-1,3-dithiane

Downstream raw materials:

C₂₉H₅₀O₃S₂