1-(3-methyl-2,4-dioxo-5,5-diphenylimidazolidin-1-yl)-3-(4-phenylpiperazin-1-yl)propan-2-yl acetate

Base Information

Chemical Name:1-(3-methyl-2,4-dioxo-5,5-diphenylimidazolidin-1-yl)-3-(4-phenylpiperazin-1-yl)propan-2-yl acetate
CAS No.:1350707-24-2
Molecular Formula:C₃₁H₃₄N₄O₄
Molecular Weight:526.635
Hs Code.:

Synonyms:1-(3-methyl-2,4-dioxo-5,5-diphenylimidazolidin-1-yl)-3-(4-phenylpiperazin-1-yl)propan-2-yl acetate

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Chemical Property of 1-(3-methyl-2,4-dioxo-5,5-diphenylimidazolidin-1-yl)-3-(4-phenylpiperazin-1-yl)propan-2-yl acetate

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Technology Process of 1-(3-methyl-2,4-dioxo-5,5-diphenylimidazolidin-1-yl)-3-(4-phenylpiperazin-1-yl)propan-2-yl acetate

There total 3 articles about 1-(3-methyl-2,4-dioxo-5,5-diphenylimidazolidin-1-yl)-3-(4-phenylpiperazin-1-yl)propan-2-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.5%

: 1350706-17-0
1-[2-hydroxy-3-(4-phenylpiperazin-1-yl)-propyl]-2,4-dioxo-3-methyl-5,5-diphenylimidazolidine

: 108-24-7
acetic anhydride

: 1350707-24-2
1-(3-methyl-2,4-dioxo-5,5-diphenylimidazolidin-1-yl)-3-(4-phenylpiperazin-1-yl)propan-2-yl acetate

Guidance literature:: at 0 ℃; for 48.25h; Reflux;
DOI:10.1016/j.ejmech.2011.09.032

Reference yield:

: 4224-00-4
3-methyl-5,5-diphenyl-imidazolidine-2,4-dione

: 1350707-24-2
1-(3-methyl-2,4-dioxo-5,5-diphenylimidazolidin-1-yl)-3-(4-phenylpiperazin-1-yl)propan-2-yl acetate

Guidance literature:: Multi-step reaction with 3 steps

1: N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate / acetone / 20 °C

2: Neat (no solvent); Microwave irradiation

3: 48.25 h / 0 °C / Reflux

With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; In acetone;
DOI:10.1016/j.ejmech.2011.09.032

Reference yield:

: 1041926-38-8
C₁₉H₁₈N₂O₃

: 1350707-24-2
1-(3-methyl-2,4-dioxo-5,5-diphenylimidazolidin-1-yl)-3-(4-phenylpiperazin-1-yl)propan-2-yl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: Neat (no solvent); Microwave irradiation

2: 48.25 h / 0 °C / Reflux

DOI:10.1016/j.ejmech.2011.09.032