3-Methyl-5,5-diphenylhydantoin

Base Information

• Chemical Name: 3-Methyl-5,5-diphenylhydantoin
• CAS No.: 4224-00-4
• Molecular Formula: C16H14N2O2
• Molecular Weight: 266.299
• Hs Code.: 2933990090
• Mol file: 4224-00-4.mol

Synonyms:2,4-Imidazolidinedione, 3-methyl-5,5-diphenyl-;

Chemical Property of 3-Methyl-5,5-diphenylhydantoin

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 52.90000
• Density: 1.235g/cm³
• LogP: 1.68970

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Methyl-5,5-diphenylhydantoin

There total 31 articles about 3-Methyl-5,5-diphenylhydantoin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

benzil (134-81-6) + N-Methylurea (598-50-5) → 3-methyl-5,5-diphenyl-imidazolidine-2,4-dione (4224-00-4)

Guidance literature:

With chitosan decorated Fe₃O₄ magnetic nanoparticles; In ethanol; water; at 60 ℃; for 0.125h; Green chemistry;

DOI:10.1039/c4ra06618a

Reference yield: 94.0%

1-methylparabanic acid (3659-97-0) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 3-methyl-5,5-diphenyl-imidazolidine-2,4-dione (4224-00-4)

Guidance literature:

With trifluorormethanesulfonic acid; at 100 ℃; for 2h;

Reference yield: 90.0%

phenythoin (57-41-0) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → 3-methyl-5,5-diphenyl-imidazolidine-2,4-dione (4224-00-4)

Guidance literature:

at 100 ℃; for 1h;

DOI:10.1002/bscb.19850940611

upstream raw materials:

3-methyl-5,5-diphenyl-3,5-dihydro-imidazol-4-one

chromium(lll) acetate

2,3-dimethyl-5,5-diphenyl-3,5-dihydro-imidazol-4-one

3-methyl-5,5-diphenyl-imidazolidin-4-one

Downstream raw materials:

1-acetyl-3-methyl-5,5-diphenyl-imidazolidine-2,4-dione

3-Methyl-5,5-diphenyl-dithiohydantoin

1-chloro-5,5-diphenyl-3-methylhydantoin

methylamine

Refernces

• 1、 Baranov, Vladimir V.,Kravchenko, Angelina N.,Nelyubina, Yulia V.,Vol'khina, Tatyana N.. "New aspects of reactions of methyl (thio)ureas with benzil". . p. 673 - 676. Retrieved 2021/11/26.
• 2、 Safari, Javad,Javadian, Leila. "Chitosan decorated Fe3O4 nanoparticles as a magnetic catalyst in the synthesis of phenytoin derivatives". . p. 48973 - 48979. Retrieved 2014/12/11.