1-[2-hydroxy-3-(4-phenylpiperazin-1-yl)-propyl]-2,4-dioxo-3-methyl-5,5-diphenylimidazolidine

Base Information

Chemical Name:1-[2-hydroxy-3-(4-phenylpiperazin-1-yl)-propyl]-2,4-dioxo-3-methyl-5,5-diphenylimidazolidine
CAS No.:1350706-17-0
Molecular Formula:C₂₉H₃₂N₄O₃
Molecular Weight:484.598
Hs Code.:

Synonyms:1-[2-hydroxy-3-(4-phenylpiperazin-1-yl)-propyl]-2,4-dioxo-3-methyl-5,5-diphenylimidazolidine

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Chemical Property of 1-[2-hydroxy-3-(4-phenylpiperazin-1-yl)-propyl]-2,4-dioxo-3-methyl-5,5-diphenylimidazolidine

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Technology Process of 1-[2-hydroxy-3-(4-phenylpiperazin-1-yl)-propyl]-2,4-dioxo-3-methyl-5,5-diphenylimidazolidine

There total 2 articles about 1-[2-hydroxy-3-(4-phenylpiperazin-1-yl)-propyl]-2,4-dioxo-3-methyl-5,5-diphenylimidazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 92-54-6
4-phenyl-1-piperazine

: 1041926-38-8
C₁₉H₁₈N₂O₃

: 1350706-17-0
1-[2-hydroxy-3-(4-phenylpiperazin-1-yl)-propyl]-2,4-dioxo-3-methyl-5,5-diphenylimidazolidine

Guidance literature:: for 0.216667h; Microwave irradiation; Neat (no solvent);
DOI:10.1016/j.bmc.2012.02.009

Reference yield:

: 4224-00-4
3-methyl-5,5-diphenyl-imidazolidine-2,4-dione

: 1350706-17-0
1-[2-hydroxy-3-(4-phenylpiperazin-1-yl)-propyl]-2,4-dioxo-3-methyl-5,5-diphenylimidazolidine

Guidance literature:: Multi-step reaction with 2 steps

1: N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate / acetone / 20 °C

2: Neat (no solvent); Microwave irradiation

With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; In acetone;
DOI:10.1016/j.ejmech.2011.09.032