N-(2-Mercaptoethyl)-2-phenyl-4-thiazolidinecarboxamide monohydrochloride

Base Information

Chemical Name:N-(2-Mercaptoethyl)-2-phenyl-4-thiazolidinecarboxamide monohydrochloride
CAS No.:106086-25-3
Molecular Formula:C12H16 N2 O S2 . Cl H
Molecular Weight:304.8592
Hs Code.:
DSSTox Substance ID:DTXSID80909906

Synonyms:2-Phenylthiazolidine-4-carboxylic acid beta-mercaptoethylamide hydrochloride;N-(2-Mercaptoethyl)-2-phenyl-4-thiazolidinecarboxamide monohydrochloride;4-Thiazolidinecarboxamide, N-(2-mercaptoethyl)-2-phenyl-, monohydrochloride;106086-25-3;C12H15N2OS2.ClH;DTXSID80909906;C12-H15-N2-O-S2.Cl-H;LS-151158;2-Phenyl-N-(2-sulfanylethyl)-1,3-thiazolidine-4-carboximidic acid--hydrogen chloride (1/1)

Suppliers and Price of N-(2-Mercaptoethyl)-2-phenyl-4-thiazolidinecarboxamide monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2-Mercaptoethyl)-2-phenyl-4-thiazolidinecarboxamide monohydrochloride

Chemical Property:

Vapor Pressure:1.93E-11mmHg at 25°C
Boiling Point:533°C at 760 mmHg
Flash Point:276.2°C
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:304.0470832
Heavy Atom Count:18
Complexity:257

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(NC(S1)C2=CC=CC=C2)C(=O)NCCS.Cl

Technology Process of N-(2-Mercaptoethyl)-2-phenyl-4-thiazolidinecarboxamide monohydrochloride

There total 4 articles about N-(2-Mercaptoethyl)-2-phenyl-4-thiazolidinecarboxamide monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 106086-19-5
N-tert-Butyloxycarbonyl-2-phenylthiazolidine-4-carboxylic acid β-mercaptoethylamide

: 106086-25-3
β-Mercaptoethylamide-2-phenylthiazolidine-4-carboxylic acid hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 10 ℃;
DOI:10.1007/BF01148643

Reference yield:

: 196930-46-8
(4R)-2-phenyl-1,3-thiazolidine-4-carboxylic acid

: 106086-25-3
β-Mercaptoethylamide-2-phenylthiazolidine-4-carboxylic acid hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / Et₃N / dimethylformamide / 2 h / Ambient temperature

2: 73.5 percent / dicyclohexylcarbodiimide / dimethylformamide / 2 h

3: 97 percent / N-methylmorpholine / dimethylformamide / 4 h / Ambient temperature

4: 86 percent / HCl / dioxane / 10 °C

With 4-methyl-morpholine; hydrogenchloride; triethylamine; dicyclohexyl-carbodiimide; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1007/BF01148643

Reference yield:

: 106086-10-6
(4R)-3-(tert-butoxycarbonyl)-2-phenylthiazolidine-4-carboxylic acid

: 106086-25-3
β-Mercaptoethylamide-2-phenylthiazolidine-4-carboxylic acid hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 73.5 percent / dicyclohexylcarbodiimide / dimethylformamide / 2 h

2: 97 percent / N-methylmorpholine / dimethylformamide / 4 h / Ambient temperature

3: 86 percent / HCl / dioxane / 10 °C

With 4-methyl-morpholine; hydrogenchloride; dicyclohexyl-carbodiimide; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1007/BF01148643