(E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-..

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Chemical Name:(E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-..
CAS No.:157117-34-5
Molecular Formula:C₆₁H₁₀₄O₁₂Si₂
Molecular Weight:1085.66
Hs Code.:

(E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-..

Synonyms:(E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-..

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Chemical Property of (E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-..

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Technology Process of (E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-..

There total 5 articles about (E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-.. which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 142144-24-9
(2S,3S,4S,5S,6S)-2,4,6-trimethyl-8-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,5-di-tert-butylsilylenedioxyoctanal

: 157117-34-5
(E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-..

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / TiCl₄ / CH₂Cl₂ / 0.5 h / -90 °C

2: 1.) O₃, 2.) TfOH / 1.) CH₂Cl₂, MeOH, -78 deg C, 15 min, 2.) Et₂O, 20 deg C, 1 h

3: 1.) (c-C₆H₁₁)2BCl, Et₃N, 3.) H₂O₂

With trifluorormethanesulfonic acid; dicyclohexylboron chloride; dihydrogen peroxide; titanium tetrachloride; ozone; triethylamine; In dichloromethane;
DOI:10.1021/ja00085a050

Reference yield:

: 152036-84-5
(E,E,7S)-methyl-8-<(2R,6S)-6-formylmethyl-5,6-dihydro-2H-pyran-2-yl>-7-(tert-butyldimethylsilyloxy)-4-methylocta-2,4-dienoate

: 157117-32-3
(5R,6S,7S,8S,9S,10S)-7,9-(di-tert-butylsilylenedioxy)-6,8,10-trimethyl-5-(para-methoxybenzyloxy)-12-((2S',4R',6S')-2-methyl-4-methoxytetrahydropyran-6-yl)-3-oxododecane

: 157117-34-5
(E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-..

: (E,E,7S)-methyl-8-<(2R,6S)-6-<(2S,3S,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-..

Guidance literature:: With dicyclohexylboron chloride; dihydrogen peroxide; triethylamine; Yield given. Multistep reaction. Yields of byproduct given;
DOI:10.1021/ja00085a050

Reference yield:

: 89238-99-3
O-(4-methoxybenzyl)-trichloroacetimidate

: 157117-34-5
(E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-..

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) O₃, 2.) TfOH / 1.) CH₂Cl₂, MeOH, -78 deg C, 15 min, 2.) Et₂O, 20 deg C, 1 h

2: 1.) (c-C₆H₁₁)2BCl, Et₃N, 3.) H₂O₂

With trifluorormethanesulfonic acid; dicyclohexylboron chloride; dihydrogen peroxide; ozone; triethylamine;
DOI:10.1021/ja00085a050