1-Ethyl-3-hydroxy-2-methylpyridin-4(1H)-one

Base Information

• Chemical Name: 1-Ethyl-3-hydroxy-2-methylpyridin-4(1H)-one
• CAS No.: 30652-12-1
• Molecular Formula: C₈H₁₁NO₂
• Molecular Weight: 153.181
• Hs Code.: 2933399090
• European Community (EC) Number: 806-769-6
• DSSTox Substance ID: DTXSID60184698
• Nikkaji Number: J367.137B
• Wikidata: Q83055624
• ChEMBL ID: CHEMBL70110
• Mol file: 30652-12-1.mol

Synonyms:1-EMHP-one;1-ethyl-2-methyl-3-hydroxypyrid-4-one;1-ethyl-2-methyl-3-hydroxypyridin-4-one;1-ethyl-3-hydroxy-2-methyl-4-pyridinone

Chemical Property of 1-Ethyl-3-hydroxy-2-methylpyridin-4(1H)-one

Chemical Property:

• Vapor Pressure: 0.00366mmHg at 25°C
• Melting Point: 203-206°C
• Boiling Point: 249.5°C at 760 mmHg
• PKA: 9.52±0.20(Predicted)
• Flash Point: 104.7°C
• PSA: 42.23000
• Density: 1.168g/cm³
• LogP: 0.88220
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly, Heated), Methanol (Slightly)
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 153.078978594
• Heavy Atom Count: 11
• Complexity: 241

Purity/Quality:

97% ^*data from raw suppliers

1-Ethyl-3-hydroxy-2-methyl-4-pyridinone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN1C=CC(=O)C(=C1C)O
• Uses: 1-Ethyl-3-hydroxy-2-methyl-4(1H)-pyridinone is used as iron chelating agent, it is used for the local treatment of skin microcirculatory disorders. It is used as iron chelating agent. Hydroxypyridinones are used for the local treatment of skin microcirculatory disorders.

Technology Process of 1-Ethyl-3-hydroxy-2-methylpyridin-4(1H)-one

There total 7 articles about 1-Ethyl-3-hydroxy-2-methylpyridin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

isomaltol (3420-59-5) + ethylamine (75-04-7,85404-22-4) → CP21 (30652-12-1)

Guidance literature:

In methanol; for 8h; Heating;

DOI:10.1080/00397919908086062

Reference yield: 39.0%

ethylamine (75-04-7,85404-22-4) + 3-(β-D-galactopyranosyloxy)-2-furanyl methyl ketone (82756-28-3) → CP21 (30652-12-1)

Guidance literature:

In water; for 20h; Heating;

DOI:10.1080/00397919908086062

Reference yield: 33.0%

Maltol (118-71-8) + ethylamine (75-04-7,85404-22-4) → CP21 (30652-12-1)

Guidance literature:

Heating;

DOI:10.1080/00397919908086062

upstream raw materials:

Maltol

ethylamine

isomaltol

3-(β-D-galactopyranosyloxy)-2-furanyl methyl ketone