1-(4-tolyl)thio-2,3-O-isopropylidene-4-O-(1-methoxy-1-methylethyl)-β-D-xylopyranoside

Base Information

• Chemical Name: 1-(4-tolyl)thio-2,3-O-isopropylidene-4-O-(1-methoxy-1-methylethyl)-β-D-xylopyranoside
• CAS No.: 1445703-80-9
• Molecular Formula: C₁₉H₂₈O₅S
• Molecular Weight: 368.494
• Mol file: 1445703-80-9.mol

Synonyms:1-(4-tolyl)thio-2,3-O-isopropylidene-4-O-(1-methoxy-1-methylethyl)-β-D-xylopyranoside

Chemical Property of 1-(4-tolyl)thio-2,3-O-isopropylidene-4-O-(1-methoxy-1-methylethyl)-β-D-xylopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-tolyl)thio-2,3-O-isopropylidene-4-O-(1-methoxy-1-methylethyl)-β-D-xylopyranoside

There total 1 articles about 1-(4-tolyl)thio-2,3-O-isopropylidene-4-O-(1-methoxy-1-methylethyl)-β-D-xylopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-Methoxypropene (116-11-0) + 4-methylphenyl 1-thio-β-D-xylopyranoside (67803-94-5) + 2,2-dimethoxy-propane (77-76-9) → 1-(4-tolyl)thio-2,3-O-isopropylidene-4-O-(1-methoxy-1-methylethyl)-β-D-xylopyranoside (1445703-80-9)

Guidance literature:

With trifluoroacetic acid; In N,N-dimethyl-formamide; at 40 ℃; for 12h;

DOI:10.1016/j.ejmech.2013.04.016

Reference yield: 88.0%

1-(4-tolyl)thio-2,3-O-isopropylidene-4-O-(1-methoxy-1-methylethyl)-β-D-xylopyranoside (1445703-80-9) → 1-(4-tolyl)thio-2,3-O-isopropylidene-β-D-xylopyranoside (1415218-00-6)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; at 0 ℃;

DOI:10.1016/j.ejmech.2013.04.016

Reference yield:

1-(4-tolyl)thio-2,3-O-isopropylidene-4-O-(1-methoxy-1-methylethyl)-β-D-xylopyranoside (1445703-80-9) → C17H22O5S

Guidance literature:

Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / methanol / 0 °C

2: pyridine; dmap / dichloromethane / 2 h

With pyridine; dmap; toluene-4-sulfonic acid; In methanol; dichloromethane;

DOI:10.1016/j.ejmech.2013.04.016

upstream raw materials:

2-Methoxypropene

4-methylphenyl 1-thio-β-D-xylopyranoside

2,2-dimethoxy-propane

Downstream raw materials:

1-(4-tolyl)thio-2,3-O-isopropylidene-β-D-xylopyranoside

1-(4-tolyl)thio-4-O-acetyl-β-D-xylopyranoside

1-(4-tolyl)thio-2,3-di-O-benzoyl-4-O-acetyl-β-D-xylopyranoside

4-methylphenyl 2,3-di-O-benzoyl-1-thio-β-D-xylopyranoside