2-[2,6-dimethyl-4-[[[(1-methyl-2-oxoethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester

Base Information

Chemical Name:2-[2,6-dimethyl-4-[[[(1-methyl-2-oxoethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester
CAS No.:866640-96-2
Molecular Formula:C₃₁H₃₉N₃O₆
Molecular Weight:549.667
Hs Code.:

2-[2,6-dimethyl-4-[[[(1-methyl-2-oxoethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester

Synonyms:2-[2,6-dimethyl-4-[[[(1-methyl-2-oxoethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester

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Chemical Property of 2-[2,6-dimethyl-4-[[[(1-methyl-2-oxoethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester

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Technology Process of 2-[2,6-dimethyl-4-[[[(1-methyl-2-oxoethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester

There total 2 articles about 2-[2,6-dimethyl-4-[[[(1-methyl-2-oxoethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79-37-8
oxalyl dichloride

: 866640-95-1
2-[4-[[[(2-hydroxy-1-methylethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester

: 866640-96-2
2-[2,6-dimethyl-4-[[[(1-methyl-2-oxoethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester

Guidance literature:: oxalyl dichloride; With dimethyl sulfoxide; In dichloromethane; at -78 ℃; for 0.166667h;

2-[4-[[[(2-hydroxy-1-methylethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester; In dichloromethane; for 1h;

With triethylamine; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

: 866640-95-1
2-[4-[[[(2-hydroxy-1-methylethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester

: 866640-96-2
2-[2,6-dimethyl-4-[[[(1-methyl-2-oxoethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester

Guidance literature:: 2-[4-[[[(2-hydroxy-1-methylethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid ethyl ester; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 ℃; for 1h;

With triethylamine; In dichloromethane; at -78 - 20 ℃; for 1h;

Reference yield:

: 866640-96-2
2-[2,6-dimethyl-4-[[[(1-methyl-2-oxoethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester

: 866639-97-6
2-[2,6-dimethyl-4-[[(4-methyloxazol-2-ylmethyl)(5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester

Guidance literature:: With hexachloroethane; triethylamine; triphenylphosphine; In dichloromethane; at 0 ℃; for 0.25h;

2-[2,6-dimethyl-4-[[[(1-methyl-2-oxoethylcarbamoyl)methyl](5-methyl-2-phenyloxazol-4-ylmethyl)amino]methyl]phenoxy]-2-methylpropanoic acid ethyl ester; In dichloromethane; at 0 - 20 ℃;