N-[(1E)-2,2,2-trifluoroethylidene]tricyclo[3.3.1.1~3,7~]decan-1-amine

Base Information

• Chemical Name: N-[(1E)-2,2,2-trifluoroethylidene]tricyclo[3.3.1.1~3,7~]decan-1-amine
• CAS No.: 31185-52-1
• Molecular Formula: C₁₂H₁₆F₃N
• Molecular Weight: 231.261
• Mol file: 31185-52-1.mol

Synonyms:1-Adamantanamine,N-(2,2,2-trifluoroethylidene)- (8CI)

Chemical Property of N-[(1E)-2,2,2-trifluoroethylidene]tricyclo[3.3.1.1~3,7~]decan-1-amine

Chemical Property:

• Vapor Pressure: 0.0821mmHg at 25°C
• Boiling Point: 234.1°C at 760 mmHg
• Flash Point: 95.4°C
• PSA: 12.36000
• Density: 1.4g/cm³
• LogP: 3.58830

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-[(1E)-2,2,2-trifluoroethylidene]tricyclo[3.3.1.1~3,7~]decan-1-amine

There total 2 articles about N-[(1E)-2,2,2-trifluoroethylidene]tricyclo[3.3.1.1~3,7~]decan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Adamantanamine (768-94-5) + ethyl trifluoroacetaldehyde hemiacetal (433-27-2) → N-(adamantan-1-yl)-2,2,2-trifluoroethan-1-imine (31185-52-1)

Guidance literature:

In water; at 105 ℃; for 4h;

DOI:10.1021/acs.orglett.9b00128

Reference yield:

2,2,2-Trifluoroacetaldehyde (75-90-1) + 1-Adamantanamine (768-94-5) → N-(adamantan-1-yl)-2,2,2-trifluoroethan-1-imine (31185-52-1)

Guidance literature:

In benzene;

DOI:10.1021/jm00300a044

upstream raw materials:

2,2,2-Trifluoroacetaldehyde

1-Adamantanamine

ethyl trifluoroacetaldehyde hemiacetal