1-Benzyl-3-hydroxy-4-methanesulfonyloxymethylpyrrolidine

Base Information

Chemical Name:1-Benzyl-3-hydroxy-4-methanesulfonyloxymethylpyrrolidine
CAS No.:108026-67-1
Molecular Formula:C₁₃H₁₉NO₄S
Molecular Weight:285.364
Hs Code.:
DSSTox Substance ID:DTXSID501153479

Synonyms:1-benzyl-3-hydroxy-4-methanesulfonyloxymethylpyrrolidine;SCHEMBL10511264;MBMBUSUISIGXCG-UHFFFAOYSA-N;DTXSID501153479;108026-67-1;3-Pyrrolidinemethanol, 4-hydroxy-1-(phenylmethyl)-, 3-methanesulfonate

Suppliers and Price of 1-Benzyl-3-hydroxy-4-methanesulfonyloxymethylpyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Benzyl-3-hydroxy-4-methanesulfonyloxymethylpyrrolidine

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:285.10347926
Heavy Atom Count:19
Complexity:373

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CS(=O)(=O)OCC1CN(CC1O)CC2=CC=CC=C2

Technology Process of 1-Benzyl-3-hydroxy-4-methanesulfonyloxymethylpyrrolidine

There total 3 articles about 1-Benzyl-3-hydroxy-4-methanesulfonyloxymethylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 780-15-4
1-benzyl-3-hydroxymethyl-4-hydroxypyrrolidine

: 124-63-0
methanesulfonyl chloride

: 108026-67-1
Methanesulfonic acid 1-benzyl-4-hydroxy-pyrrolidin-3-ylmethyl ester

Guidance literature:: With triethylamine; In dichloromethane;

Reference yield:

: 780-15-4
1-benzyl-3-hydroxymethyl-4-hydroxypyrrolidine

: 124-63-0
methanesulfonyl chloride

: 108026-67-1
Methanesulfonic acid 1-benzyl-4-hydroxy-pyrrolidin-3-ylmethyl ester

Guidance literature:: With triethylamine; In dichloromethane;
DOI:10.1021/jm00167a010

Reference yield:

: 788-21-6
3-hydroxy-4-ethyloxycarbonyl-1-phenylmethyl pyrrolidine

: 108026-67-1
Methanesulfonic acid 1-benzyl-4-hydroxy-pyrrolidin-3-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; sodium borohydrid / methanol

2: triethylamine / dichloromethane

With hydrogenchloride; sodium borohydrid; triethylamine; In methanol; dichloromethane;