C₂₂H₁₉ClF₆N₂O₅

Base Information

• Chemical Name: C₂₂H₁₉ClF₆N₂O₅
• CAS No.: 895525-74-3
• Molecular Formula: C₂₂H₁₉ClF₆N₂O₅
• Molecular Weight: 540.847
• Mol file: 895525-74-3.mol

Synonyms:C₂₂H₁₉ClF₆N₂O₅

Chemical Property of C₂₂H₁₉ClF₆N₂O₅

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of C₂₂H₁₉ClF₆N₂O₅

There total 2 articles about C₂₂H₁₉ClF₆N₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.5%

{[2-(trifluoromethyl)benzoyl]amino}methyl acetate (895525-72-1) + diethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)malonate (172527-71-8) → C22H19ClF6N2O5 (895525-74-3)

Guidance literature:

With potassium carbonate; carbonic acid dimethyl ester; at 90 - 95 ℃; for 5h;

Reference yield:

2-trifluoromethylbenzoic acid (433-97-6) → C22H19ClF6N2O5 (895525-74-3)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / 80 - 85 °C

2: potassium carbonate / 1,2-dichloro-ethane / 5 h / 50 - 55 °C

3: potassium carbonate; carbonic acid dimethyl ester / 5 h / 90 - 95 °C

With thionyl chloride; potassium carbonate; carbonic acid dimethyl ester; In 1,2-dichloro-ethane;

Reference yield: 96.0%

C22H19ClF6N2O5 (895525-74-3) → fluopyram (658066-35-4)

Guidance literature:

With trifluorormethanesulfonic acid; In tert-butyl alcohol; at 126 - 127 ℃; for 4h; under 3000.3 Torr; Autoclave;

upstream raw materials:

{[2-(trifluoromethyl)benzoyl]amino}methyl acetate

diethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)malonate

2-trifluoromethylbenzoic acid

Downstream raw materials:

fluopyram