895525-72-1

Basic information

• Product Name: {[2-(trifluoromethyl)benzoyl]amino}methyl acetate
• Synonyms: {[2-(trifluoromethyl)benzoyl]amino}methyl acetate
• CAS NO: 895525-72-1
• Molecular Weight: 261.201
• Mol File: 895525-72-1.mol
• Article Data: 5

Chemical Properties

• Density: 1.44 at 20℃
• CAS DataBase Reference: {[2-(trifluoromethyl)benzoyl]amino}methyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: {[2-(trifluoromethyl)benzoyl]amino}methyl acetate(895525-72-1)
• EPA Substance Registry System: {[2-(trifluoromethyl)benzoyl]amino}methyl acetate(895525-72-1)

Safety Data

• Hazardous Substances Data: 895525-72-1(Hazardous Substances Data)

Usage

General Description

The chemical compound {[2-(trifluoromethyl)benzoyl]amino}methyl acetate, also known as TFMA, is an organic compound with the molecular formula C11H10F3NO3. It is a white crystalline solid that is commonly used as a reagent in chemical synthesis. TFMA is a derivative of benzoylamine and is used in the pharmaceutical and agrochemical industries as a building block for the synthesis of various compounds. It is also used as a protecting group for amines in organic synthesis. TFMA is considered to be stable under normal conditions and is not known to be hazardous to health, making it a versatile and valuable compound in synthetic chemistry.

Upstream product

• 312-94-7 2-trifluoromethylbenzoyl chloride 
• 360-64-5 2-(trifluoromethyl)benzamide 
• 433-97-6 2-trifluoromethylbenzoic acid 
• 630117-94-1 N-[2-(trifluoromethyl)benzoyl] glycine 

Downstream Products

• 895525-76-5 dimethyl [3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)benzoyl]amino}methyl)malonate 
• 895525-74-3 C₂₂H₁₉ClF₆N₂O₅ 

Relevant articles and documents

Synthesis method of fluopyram intermediate

The invention discloses a synthesis method of a fluopyram intermediate, and belongs to the field of organic synthesis of pesticides. The process comprises the following steps: by taking methanol amine as a starting raw material, carrying out esterification reaction on methanol amine and acetic anhydride in the presence of acetic acid to obtain methyl aminoacetate, and carrying out amidation reaction on methyl aminoacetate and o-trifluoromethyl benzoyl chloride to obtain N-acetoxymethyl-2-trifluoromethyl benzamide; and finally, carrying out a splicing reaction with diethyl 3-chloro-5-trifluoromethyl-2-pyridylmalonate, so as to obtain the 3-chloro-5-trifluoromethyl-2-pyridylethyl (diethyl ester)-2-trifluoromethyl benzamide. The method adopts a convergent synthesis route, has the characteristics of low raw material cost, high atom economy, high yield, simple process operation and the like, and is suitable for large-scale production.

Acetamides and benzamides that are useful in treating sexual dysfunction

The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.

Acetamides and benzamides that are useful in treating sexual dysfunction

The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.