Technology Process of ethyl (3-{[4'-(2-acetoxyethoxy)-2,2',6'-trimethylbiphenyl-3-yl]methoxy}-9H-fluoren-9-yl)acetate
There total 11 articles about ethyl (3-{[4'-(2-acetoxyethoxy)-2,2',6'-trimethylbiphenyl-3-yl]methoxy}-9H-fluoren-9-yl)acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium phosphate / palladium diacetate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / toluene; water / 2 h / 70 °C / Inert atmosphere
2.1: lithium aluminium tetrahydride; Glauber's salt / tetrahydrofuran / 1.33 h / 20 °C / Under cooling with ice; Inert atmosphere
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 20 - 50 °C
4.1: zinc / tetrahydrofuran / 80 °C / Inert atmosphere
4.2: 20 - 50 °C
5.1: hydrogenchloride; caesium carbonate / ethanol; water; tetrahydrofuran / 20 - 50 °C
5.2: 4 h / 50 °C
6.1: hydrogen / palladium 10% on activated carbon / ethanol; water / 4 h / 20 °C / 1474.5 Torr
With
hydrogenchloride; potassium phosphate; lithium aluminium tetrahydride; Glauber's salt; hydrogen; sodium hydride; caesium carbonate;
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium 10% on activated carbon; palladium diacetate; zinc;
In
tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide; toluene; mineral oil;
- Guidance literature:
-
With
hydrogen;
palladium 10% on activated carbon;
In
ethanol; water;
at 20 ℃;
for 4h;
under 1474.5 Torr;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 20 - 50 °C
2.1: zinc / tetrahydrofuran / 80 °C / Inert atmosphere
2.2: 20 - 50 °C
3.1: hydrogenchloride; caesium carbonate / ethanol; water; tetrahydrofuran / 20 - 50 °C
3.2: 4 h / 50 °C
4.1: hydrogen / palladium 10% on activated carbon / ethanol; water / 4 h / 20 °C / 1474.5 Torr
With
hydrogenchloride; hydrogen; sodium hydride; caesium carbonate;
palladium 10% on activated carbon; zinc;
In
tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide; mineral oil;
