tert-butyl-(2-chloro-3-trifluoromethyl-phenoxy)-dimethyl-silane

Base Information

• Chemical Name: tert-butyl-(2-chloro-3-trifluoromethyl-phenoxy)-dimethyl-silane
• CAS No.: 1202643-69-3
• Molecular Formula: C₁₃H₁₈ClF₃OSi
• Molecular Weight: 310.819
• Mol file: 1202643-69-3.mol

Synonyms:tert-butyl-(2-chloro-3-trifluoromethyl-phenoxy)-dimethyl-silane

Chemical Property of tert-butyl-(2-chloro-3-trifluoromethyl-phenoxy)-dimethyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of tert-butyl-(2-chloro-3-trifluoromethyl-phenoxy)-dimethyl-silane

There total 1 articles about tert-butyl-(2-chloro-3-trifluoromethyl-phenoxy)-dimethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

tert-butyldimethylsilyl chloride (18162-48-6) + 2-chloro-3-(trifluoromethyl)phenol (138377-34-1) → tert-butyl-(2-chloro-3-trifluoromethyl-phenoxy)-dimethyl-silane (1202643-69-3)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

tert-butyl-(2-chloro-3-trifluoromethyl-phenoxy)-dimethyl-silane (1202643-69-3) + cyclopropylboronic acid (411235-57-9) → tert-butyl-(2-cyclopropyl-3-trifluoromethyl-phenoxy)-dimethyl-silane (1202643-71-7)

Guidance literature:

With potassium phosphate; tricyclohexylphosphine; palladium diacetate; In water; toluene; at 110 ℃; for 3h;

upstream raw materials:

tert-butyldimethylsilyl chloride

2-chloro-3-(trifluoromethyl)phenol

Downstream raw materials:

tert-butyl-(2-cyclopropyl-3-trifluoromethyl-phenoxy)-dimethyl-silane