Phosphoric acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl ester methyl ester

Base Information

Chemical Name:Phosphoric acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl ester methyl ester
CAS No.:117854-40-7
Molecular Formula:C₄₀H₄₁N₆O₈P
Molecular Weight:764.775
Hs Code.:

Phosphoric acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl ester methyl ester

Synonyms:Phosphoric acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl ester methyl ester

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Chemical Property of Phosphoric acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl ester methyl ester

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Technology Process of Phosphoric acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl ester methyl ester

There total 5 articles about Phosphoric acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl ester methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 117824-86-9
Benzoic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[methoxy-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethoxy)-phosphoryloxymethyl]-tetrahydro-furan-3-yl ester

: 117854-40-7
Phosphoric acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl ester methyl ester

Guidance literature:: With sodium hydroxide; In pyridine; methanol; water; at 0 ℃; for 0.166667h;
DOI:10.1248/cpb.36.1386

Reference yield:

: 113019-11-7
2-(((4-methoxyphenyl)diphenylmethyl)amino)ethanol

: 117854-40-7
Phosphoric acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl ester methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1H-tetrazole, I₂

2: 75 percent / NaOH / methanol; pyridine; H₂O / 0.17 h / 0 °C

With 1H-tetrazole; sodium hydroxide; iodine; In pyridine; methanol; water;
DOI:10.1248/cpb.36.1386

Reference yield:

: 51549-54-3
3'-O-benzoyl-6-N-benzoyl-2'-deoxyadenosine

: 117854-40-7
Phosphoric acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl ester methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / diisopropylamine hydrotetrazolide / CH₂Cl₂ / 1 h / 30 °C

2: 1H-tetrazole, I₂

3: 75 percent / NaOH / methanol; pyridine; H₂O / 0.17 h / 0 °C

With 1H-tetrazole; sodium hydroxide; N,N-diisopropylamine tetrazolide; iodine; In pyridine; methanol; dichloromethane; water;
DOI:10.1248/cpb.36.1386