phosphoric acid-(2-benzyloxycarbonylamino-ethyl ester)-((R)-2,3-bis-palmitoyloxy-propyl ester)-phenyl ester

Base Information

• Chemical Name: phosphoric acid-(2-benzyloxycarbonylamino-ethyl ester)-((R)-2,3-bis-palmitoyloxy-propyl ester)-phenyl ester
• CAS No.: 22500-93-2
• Molecular Formula: C₅₁H₈₄NO₁₀P
• Molecular Weight: 902.202

Synonyms:phosphoric acid-(2-benzyloxycarbonylamino-ethyl ester)-((R)-2,3-bis-palmitoyloxy-propyl ester)-phenyl ester

Chemical Property of phosphoric acid-(2-benzyloxycarbonylamino-ethyl ester)-((R)-2,3-bis-palmitoyloxy-propyl ester)-phenyl ester

Chemical Property:

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Technology Process of phosphoric acid-(2-benzyloxycarbonylamino-ethyl ester)-((R)-2,3-bis-palmitoyloxy-propyl ester)-phenyl ester

There total 2 articles about phosphoric acid-(2-benzyloxycarbonylamino-ethyl ester)-((R)-2,3-bis-palmitoyloxy-propyl ester)-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O-phenyl phosphorodichloridate (770-12-7) → phosphoric acid-(2-benzyloxycarbonylamino-ethyl ester)-((R)-2,3-bis-palmitoyloxy-propyl ester)-phenyl ester (22500-93-2)

Guidance literature:

With pyridine; chloroform; Behandeln der Reaktionsloesung mit <2-Hydroxy-aethyl>-carbamidsaeure-benzylester und Pyridin;

DOI:10.1021/ja01121a038

Reference yield:

→ Hexadecanoic acid 2-[(2-benzyloxycarbonylamino-ethoxy)-phenoxy-phosphoryloxy]-1-hexadecanoyloxymethyl-ethyl ester (22500-93-2)

Guidance literature:

Bromhydrin IV, Phenylphosphoryl-N-carbobenzoxyethanolamin-Ag-salz, MeCN;

DOI:10.1016/0009-3084(68)90015-7

Reference yield:

phosphoric acid-(2-benzyloxycarbonylamino-ethyl ester)-((R)-2,3-bis-palmitoyloxy-propyl ester)-phenyl ester (22500-93-2) → 1,2-dipalmitoyl-3-sn-phosphatidylethanolamine (923-61-5,3026-45-7)

Guidance literature:

With palladium platinum; acetic acid; Hydrogenation;

DOI:10.1021/ja01121a038

upstream raw materials:

O-phenyl phosphorodichloridate

Downstream raw materials:

1,2-dipalmitoyl-3-sn-phosphatidylethanolamine

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