Technology Process of FAC
There total 6 articles about FAC which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
N-benzyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide;
With
sodium hydride;
In
N,N-dimethyl-formamide;
for 0.166667h;
Inert atmosphere;
Cooling with ice;
2-fluoroethyl bromide;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 1h;
Inert atmosphere;
DOI:10.1002/bkcs.10979
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine; diphenyl phosphoryl azide / N,N-dimethyl-formamide / 2 h / 100 °C / Inert atmosphere
2.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere; Cooling with ice
3.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / Inert atmosphere; Cooling with ice
3.2: 1 h / 20 °C / Inert atmosphere
With
diphenyl phosphoryl azide; sodium hydride; potassium carbonate; triethylamine;
In
N,N-dimethyl-formamide;
DOI:10.1002/bkcs.10979
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere; Cooling with ice
2.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / Inert atmosphere; Cooling with ice
2.2: 1 h / 20 °C / Inert atmosphere
With
sodium hydride; potassium carbonate;
In
N,N-dimethyl-formamide;
DOI:10.1002/bkcs.10979
