2-Amino-4-methylpentan-1-ol

Base Information

• Chemical Name: 2-Amino-4-methylpentan-1-ol
• CAS No.: 502-32-9
• Molecular Formula: C₆H₁₅NO
• Molecular Weight: 117.191
• European Community (EC) Number: 207-933-4
• NSC Number: 64339
• DSSTox Substance ID: DTXSID40936859
• Nikkaji Number: J11.780C
• Mol file: 502-32-9.mol

Synonyms:2-Amino-4-methylpentan-1-ol;502-32-9;DL-Leucinol;1-Pentanol, 2-amino-4-methyl-;16369-17-8;EINECS 207-933-4;MFCD00066926;2-Amino-4-methyl-pentan-1-ol;H-Leu-ol;H-D-Leu-ol;D/L-Leucinol;2-Amino-4-methyl-1-pentanol #;2-Amino-4-methyl-1-pentanol;MFCD00063676;NSC64339;(+/-)-Leucinol;SCHEMBL143927;l-2-Amino-4-methyl-1-pentanol;DTXSID40936859;NSC-64339;AKOS008105072;CS-W021562;DS-3187;SY014112;SY030474;SY030475;2-amino-4-methylpentan-1-ol, AldrichCPR;FT-0625459;FT-0627938;EN300-53336;A871631;Z734151210

Chemical Property of 2-Amino-4-methylpentan-1-ol

Chemical Property:

• Vapor Pressure: 0.0897mmHg at 25°C
• Boiling Point: 198.6°Cat760mmHg
• PKA: 12.88±0.10(Predicted)
• Flash Point: 90.6°C
• PSA: 46.25000
• Density: 0.904g/cm³
• LogP: 1.05240
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 117.115364102
• Heavy Atom Count: 8
• Complexity: 54.5

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-4-methylpentan-1-ol >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)CC(CO)N

Technology Process of 2-Amino-4-methylpentan-1-ol

There total 9 articles about 2-Amino-4-methylpentan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

→ 2-amino-4-methyl-1-pentanol (7533-40-6,16369-17-8,53448-09-2,502-32-9,14438-11-0)

Guidance literature:

Reference yield: 83.0%

(R)-leucine methyl ester hydrochloride (5845-53-4,6322-53-8,7517-19-3) → 2-amino-4-methyl-1-pentanol (7533-40-6,16369-17-8,53448-09-2,502-32-9,14438-11-0)

Guidance literature:

With sodium tetrahydroborate; In ethanol; water; for 5.5h; Heating;

Reference yield: 76.0%

D-leucine methyl ester (23032-21-5) → 2-amino-4-methyl-1-pentanol (7533-40-6,16369-17-8,53448-09-2,502-32-9,14438-11-0)

Guidance literature:

With sodium tetrahydroborate;

upstream raw materials:

ethyl N-acetyl-leucinate

D-leucine ethyl ester

(R)-leucine

D-leucine methyl ester

Downstream raw materials:

(R)-2-amino-1-bromo-4-methylpentane hydrobromide

(R)-4-Methyl-2-{[1-phenyl-meth-(E)-ylidene]-amino}-pentan-1-ol

(R)-2-{[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-amino}-4-methyl-pentan-1-ol

Toluene-4-sulfonic acid (R)-4-methyl-2-(toluene-4-sulfonylamino)-pentyl ester