(E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 4-carbamimidoyl-phenyl ester

Base Information

• Chemical Name: (E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 4-carbamimidoyl-phenyl ester
• CAS No.: 112021-85-9
• Molecular Formula: C₁₇H₁₆N₂O₃
• Molecular Weight: 296.326
• Mol file: 112021-85-9.mol

Synonyms:(E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 4-carbamimidoyl-phenyl ester

Chemical Property of (E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 4-carbamimidoyl-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 4-carbamimidoyl-phenyl ester

There total 3 articles about (E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 4-carbamimidoyl-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

salicylaldehyde (90-02-8) → (E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 4-carbamimidoyl-phenyl ester (112021-85-9)

Guidance literature:

Multi-step reaction with 3 steps

2: H₂O, base

3: DCC

With water; dicyclohexyl-carbodiimide;

DOI:10.1021/ja00238a062

Reference yield:

p-hydroxybenzamidine (15535-98-5) + (E)-3-(2-hydroxyphenyl)-2-methylacrylic acid (103487-44-1) → (E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 4-carbamimidoyl-phenyl ester (112021-85-9)

Guidance literature:

With dicyclohexyl-carbodiimide;

DOI:10.1021/ja00238a062

Reference yield:

ethyl (E)-3-(2-hydroxyphenyl)-2-methylacrylate (112021-87-1) → (E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 4-carbamimidoyl-phenyl ester (112021-85-9)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂O, base

2: DCC

With water; dicyclohexyl-carbodiimide;

DOI:10.1021/ja00238a062

upstream raw materials:

p-hydroxybenzamidine

(E)-3-(2-hydroxyphenyl)-2-methylacrylic acid

salicylaldehyde

ethyl (E)-3-(2-hydroxyphenyl)-2-methylacrylate

Downstream raw materials:

3-methylcoumarine