3-(tert-Butylamino)-1-(2,4-dimethyl-6-(1-(1H-imidazol-1-yl)vinyl)phenoxy)-2-propanol

Base Information

Chemical Name:3-(tert-Butylamino)-1-(2,4-dimethyl-6-(1-(1H-imidazol-1-yl)vinyl)phenoxy)-2-propanol
CAS No.:85128-21-8
Molecular Formula:C₂₀H₂₉N₃O₂
Molecular Weight:343.469
Hs Code.:
DSSTox Substance ID:DTXSID501005545
ChEMBL ID:CHEMBL15454

Synonyms:BRN 5589260;2-Propanol, 3-(tert-butylamino)-1-(2,4-dimethyl-6-(1-(1H-imidazol-1-yl)vinyl)phenoxy)-;3-(tert-Butylamino)-1-(2,4-dimethyl-6-(1-(1H-imidazol-1-yl)vinyl)phenoxy)-2-propanol;85128-21-8;CHEMBL15454;DTXSID501005545;LS-121836;1-(tert-Butylamino)-3-{2-[1-(1H-imidazol-1-yl)ethenyl]-4,6-dimethylphenoxy}propan-2-ol

Suppliers and Price of 3-(tert-Butylamino)-1-(2,4-dimethyl-6-(1-(1H-imidazol-1-yl)vinyl)phenoxy)-2-propanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(tert-Butylamino)-1-(2,4-dimethyl-6-(1-(1H-imidazol-1-yl)vinyl)phenoxy)-2-propanol

Chemical Property:

Vapor Pressure:1.53E-12mmHg at 25°C
Boiling Point:541.1°C at 760 mmHg
Flash Point:281°C
Density:1.06g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:343.22597718
Heavy Atom Count:25
Complexity:435

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)C(=C)N2C=CN=C2)OCC(CNC(C)(C)C)O)C

Technology Process of 3-(tert-Butylamino)-1-(2,4-dimethyl-6-(1-(1H-imidazol-1-yl)vinyl)phenoxy)-2-propanol

There total 2 articles about 3-(tert-Butylamino)-1-(2,4-dimethyl-6-(1-(1H-imidazol-1-yl)vinyl)phenoxy)-2-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1-[1-(3,5-Dimethyl-2-oxiranylmethoxy-phenyl)-vinyl]-1H-imidazole

: 75-64-9
tert-butylamine

: 85128-21-8
1-tert-Butylamino-3-[2-(1-imidazol-1-yl-vinyl)-4,6-dimethyl-phenoxy]-propan-2-ol

Guidance literature:: at 50 ℃; for 19h;
DOI:10.1021/jm00375a010

Reference yield:

: 85128-46-7
2-(1-Imidazol-1-yl-vinyl)-4,6-dimethyl-phenol

: 85128-21-8
1-tert-Butylamino-3-[2-(1-imidazol-1-yl-vinyl)-4,6-dimethyl-phenoxy]-propan-2-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, RT, 5 min, 2.) DMF, 40 deg C, 1 h

2: 50 percent / 19 h / 50 °C

With sodium hydride;
DOI:10.1021/jm00375a010