2-(5-AMINO-[1,3,4]THIADIAZOL-2-YLSULFANYL)-1-(4-FLUORO-PHENYL)-ETHANONE

Base Information

Chemical Name:2-(5-AMINO-[1,3,4]THIADIAZOL-2-YLSULFANYL)-1-(4-FLUORO-PHENYL)-ETHANONE
CAS No.:401584-21-2
Molecular Formula:C₁₀H₈FN₃OS₂
Molecular Weight:269.323
Hs Code.:
Mol file:401584-21-2.mol

Synonyms:2-((5-amino-1,3,4-thiadiazol-2-yl)thio)-1-(4-fluorophenyl)ethanone

Suppliers and Price of 2-(5-AMINO-[1,3,4]THIADIAZOL-2-YLSULFANYL)-1-(4-FLUORO-PHENYL)-ETHANONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-[(5-AMINO-1,3,4-THIADIAZOL-2-YL)SULFANYL]-1-(4-FLUOROPHENYL)ETHANONE 95.00%
5MG
$ 499.29

Total 0 raw suppliers

Chemical Property of 2-(5-AMINO-[1,3,4]THIADIAZOL-2-YLSULFANYL)-1-(4-FLUORO-PHENYL)-ETHANONE

Chemical Property:

Melting Point:178-179 °C
Boiling Point:482.6±51.0 °C(Predicted)
PKA:2.03±0.10(Predicted)
Density:1.51±0.1 g/cm3(Predicted)

Purity/Quality:: 2-[(5-AMINO-1,3,4-THIADIAZOL-2-YL)SULFANYL]-1-(4-FLUOROPHENYL)ETHANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 2-(5-AMINO-[1,3,4]THIADIAZOL-2-YLSULFANYL)-1-(4-FLUORO-PHENYL)-ETHANONE

There total 3 articles about 2-(5-AMINO-[1,3,4]THIADIAZOL-2-YLSULFANYL)-1-(4-FLUORO-PHENYL)-ETHANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 2349-67-9
2-Amino-5-mercapto-1,3,4-thiadiazole

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 401584-21-2
2-((5-amino-1,3,4-thiadiazol-2-yl)thio)-1-(4-fluorophenyl)ethanone

Guidance literature:: 2-Amino-5-mercapto-1,3,4-thiadiazole; With potassium hydroxide; In ethanol; at 20 ℃; for 0.5h;

2-bromo-4'-fluoroacetophenone; In ethanol; Reflux;
DOI:10.1002/minf.201700083

Reference yield:

: 2349-67-9
2-Amino-5-mercapto-1,3,4-thiadiazole

: 401584-21-2
2-((5-amino-1,3,4-thiadiazol-2-yl)thio)-1-(4-fluorophenyl)ethanone

Guidance literature:: With Amberlite IRA-67; In N,N-dimethyl-formamide; at 20 ℃; for 1.5h;
DOI:10.1002/cmdc.201000066

Reference yield:

: 403-42-9
1-(4-fluorophenyl)ethanone

: 401584-21-2
2-((5-amino-1,3,4-thiadiazol-2-yl)thio)-1-(4-fluorophenyl)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride; bromine

2: potassium hydroxide / water; ethanol / 4 h / 20 °C

With aluminum (III) chloride; bromine; potassium hydroxide; In ethanol; water;
DOI:10.1007/s00044-012-0074-2