N,N-bis-[2-tert-butoxycarbonylaminoacetyl-(2-aminoethyl)]-5-(methylamino)-2,4,6-triiodoisophthalic acid amide

Base Information

• Chemical Name: N,N-bis-[2-tert-butoxycarbonylaminoacetyl-(2-aminoethyl)]-5-(methylamino)-2,4,6-triiodoisophthalic acid amide
• CAS No.: 869339-45-7
• Molecular Formula: C₂₇H₄₀I₃N₇O₈
• Molecular Weight: 971.37
• Mol file: 869339-45-7.mol

Synonyms:N,N-bis-[2-tert-butoxycarbonylaminoacetyl-(2-aminoethyl)]-5-(methylamino)-2,4,6-triiodoisophthalic acid amide

Chemical Property of N,N-bis-[2-tert-butoxycarbonylaminoacetyl-(2-aminoethyl)]-5-(methylamino)-2,4,6-triiodoisophthalic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-bis-[2-tert-butoxycarbonylaminoacetyl-(2-aminoethyl)]-5-(methylamino)-2,4,6-triiodoisophthalic acid amide

There total 1 articles about N,N-bis-[2-tert-butoxycarbonylaminoacetyl-(2-aminoethyl)]-5-(methylamino)-2,4,6-triiodoisophthalic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,4,6-triiodo-5-(methylamino)isophthaloyl dichloride (76350-18-0) + tert-butyl (2-((2-aminoethyl)amino)-2-oxoethyl)carbamate (167861-58-7) → N,N-bis-[2-tert-butoxycarbonylaminoacetyl-(2-aminoethyl)]-5-(methylamino)-2,4,6-triiodoisophthalic acid amide (869339-45-7)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 15h;

Reference yield: 96.0%

N,N-bis-[2-tert-butoxycarbonylaminoacetyl-(2-aminoethyl)]-5-(methylamino)-2,4,6-triiodoisophthalic acid amide (869339-45-7) → N,N-bis-[2-(2-aminoacetylamino)ethyl]-5-(methylamino)-2,4,6-triiodoisophthalic acid amide (869339-46-8)

Guidance literature:

N,N-bis-[2-tert-butoxycarbonylaminoacetyl-(2-aminoethyl)]-5-(methylamino)-2,4,6-triiodoisophthalic acid amide; With trifluoroacetic acid; at 20 ℃; for 3h;

With sodium hydroxide; In dichloromethane; water; pH=10;

upstream raw materials:

2,4,6-triiodo-5-(methylamino)isophthaloyl dichloride

tert-butyl (2-((2-aminoethyl)amino)-2-oxoethyl)carbamate

Downstream raw materials:

N,N-bis-[2-(2-aminoacetylamino)ethyl]-5-(methylamino)-2,4,6-triiodoisophthalic acid amide