(N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)Li(THF)2

Base Information

• Chemical Name: (N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)Li(THF)2
• CAS No.: 599205-14-8
• Molecular Formula: C₃₈H₄₇LiNO₂P
• Molecular Weight: 587.711
• Mol file: 599205-14-8.mol

Synonyms:(N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)Li(THF)2

Chemical Property of (N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)Li(THF)2

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)Li(THF)2

There total 1 articles about (N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)Li(THF)2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + n-butyllithium (109-72-8,29786-93-4) + N-[2-(diphenylphosphino)phenyl]-2,6-diisopropylaniline (599205-16-0) → (N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)Li(THF)2 (599205-14-8)

Guidance literature:

at -35 - 20 ℃; for 3h;

Reference yield: 98.7%

(N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)Li(THF)2 (599205-14-8) + bis(benzonitrile)palladium(II) dichloride (15617-18-2,39958-10-6,14220-64-5) → [(N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)PdCl]2 (844611-77-4)

Guidance literature:

In tetrahydrofuran; under N2 atm. to soln. (PdCl2(PhCN)2) in THF at -35°C soln. (N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)Li(THF)2 in THF was added, react. mixt. was allowed to warm to room temp. and stirred for 1 h; soln. was evapd. to dryness in vacuo, residue was extd. with CH2Cl2, filtered and evapd. in vacuo, residue was washed with pentane; elem. anal.;

DOI:10.1021/om0492395

Reference yield: 98.1%

(N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)Li(THF)2 (599205-14-8) + aluminium trichloride (7446-70-0) → [N-(2-diphenylphosphinophenyl)-2,6-diisopropylanilide]AlCl2

Guidance literature:

In toluene; under N2 atm. AlCl3 was added at -35°C to soln. (N-(2-phenylphosphinophenyl)-2,6-diisopropylanilide)Li(THF)2 in toluene and stirred at room temp. for 4 days; react. mixt. was filtered, soln. was concd., ppt. was filtered and driedin vacuo;

DOI:10.1021/ic035373q

upstream raw materials:

tetrahydrofuran

n-butyllithium

N-[2-(diphenylphosphino)phenyl]-2,6-diisopropylaniline

Downstream raw materials:

((((CH₃)2CH)2C₆H₃NC₆H₄P(C₆H₅)2)NiCl)2

[2,6-(i-Pr)2C6H3NC6H4PPh2]Ni(η3-benzyl)

[(N-(2-(diphenylphosphino)phenyl)-2,6-diisopropylanilide)PdCl]2

(((CH₃)2CH)2C₆H₃NC₆H₄P(C₆H₅)2)NiCl(P(CH₃)3)