(4S,5R)-4-[1,3]Dithian-2-ylmethyl-2-phenyl-[1,3]dioxan-5-ol

Base Information

• Chemical Name: (4S,5R)-4-[1,3]Dithian-2-ylmethyl-2-phenyl-[1,3]dioxan-5-ol
• CAS No.: 807617-30-7
• Molecular Formula: C₁₅H₂₀O₃S₂
• Molecular Weight: 312.454
• Mol file: 807617-30-7.mol

Synonyms:(4S,5R)-4-[1,3]Dithian-2-ylmethyl-2-phenyl-[1,3]dioxan-5-ol

Chemical Property of (4S,5R)-4-[1,3]Dithian-2-ylmethyl-2-phenyl-[1,3]dioxan-5-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4S,5R)-4-[1,3]Dithian-2-ylmethyl-2-phenyl-[1,3]dioxan-5-ol

There total 1 articles about (4S,5R)-4-[1,3]Dithian-2-ylmethyl-2-phenyl-[1,3]dioxan-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzaldehyde dimethyl acetal (1125-88-8) + 2-deoxy-D-erythro-pentose cyclic 1,3-propanediyl mercaptal (50907-65-8) → (4S,5R)-4-[1,3]Dithian-2-ylmethyl-2-phenyl-[1,3]dioxan-5-ol (807617-30-7)

Guidance literature:

With camphor-10-sulfonic acid; In ethyl acetate; at 20 ℃; for 16h;

DOI:10.1021/ja0449269

Reference yield: 95.0%

(R)-ethynyl-p-tolyl-sulfoxide (99930-83-3) + (4S,5R)-4-[1,3]Dithian-2-ylmethyl-2-phenyl-[1,3]dioxan-5-ol (807617-30-7) → C24H28O4S3

Guidance literature:

With 4-methyl-morpholine; In tetrahydrofuran; at 20 ℃;

DOI:10.3987/COM-08-S(F)100

Reference yield:

propynoic acid ethyl ester (623-47-2) + (4S,5R)-4-[1,3]Dithian-2-ylmethyl-2-phenyl-[1,3]dioxan-5-ol (807617-30-7) → (E)-3-((4S,5R)-4-[1,3]Dithian-2-ylmethyl-2-phenyl-[1,3]dioxan-5-yloxy)-acrylic acid ethyl ester (807617-31-8)

Guidance literature:

With 4-methyl-morpholine; In dichloromethane; at 20 ℃; for 4h;

DOI:10.1021/ja0449269

upstream raw materials:

benzaldehyde dimethyl acetal

2-deoxy-D-erythro-pentose cyclic 1,3-propanediyl mercaptal

Downstream raw materials:

(E)-3-((4S,5R)-4-[1,3]Dithian-2-ylmethyl-2-phenyl-[1,3]dioxan-5-yloxy)-acrylic acid ethyl ester

((4aR,6S,7R,8aS)-7-Hydroxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-acetic acid ethyl ester

(E)-3-[(4S,5R)-4-(2-Oxo-ethyl)-2-phenyl-[1,3]dioxan-5-yloxy]-acrylic acid ethyl ester

(4aR,6R,7S,8aR,9aS,10aS)-7-Methyl-2-phenyl-7-vinyl-octahydro-1,3,8,10-tetraoxa-anthracen-6-ol