Ethyl propiolate

Base Information Edit

Chemical Name:Ethyl propiolate
CAS No.:623-47-2
Molecular Formula:C5H6O2
Molecular Weight:98.1014
Hs Code.:29161980
European Community (EC) Number:210-795-8
NSC Number:60551
UNII:W235G5U52S
DSSTox Substance ID:DTXSID80211359
Nikkaji Number:J137.953D
Wikipedia:Ethyl_propiolate
Wikidata:Q27122726
Metabolomics Workbench ID:57850
ChEMBL ID:CHEMBL53384
Mol file:623-47-2.mol

Synonyms:ethyl propiolate

Suppliers and Price of Ethyl propiolate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
EthylPropargylate
100g
$ 275.00

TRC
EthylPropargylate
25g
$ 120.00

TCI Chemical
Ethyl Propiolate >98.0%(GC)
25mL
$ 118.00

TCI Chemical
Ethyl Propiolate >98.0%(GC)
5mL
$ 40.00

SynQuest Laboratories
Ethyl prop-2-ynoate 99%
250 g
$ 576.00

SynQuest Laboratories
Ethyl prop-2-ynoate 99%
25 g
$ 128.00

SynQuest Laboratories
Ethyl prop-2-ynoate 99%
100 g
$ 304.00

Sigma-Aldrich
Ethyl propiolate 99%
100g
$ 226.00

Sigma-Aldrich
Ethyl propiolate 99%
5g
$ 45.70

Sigma-Aldrich
Ethyl propiolate 99%
25g
$ 116.00

Total 124 raw suppliers

Chemical Property of Ethyl propiolate Edit

Chemical Property:

Appearance/Colour:clear colorless to pale yellow liquid
Vapor Pressure:15.5mmHg at 25°C
Melting Point:9 °C
Refractive Index:n20/D 1.412(lit.)
Boiling Point:119.999 °C at 760 mmHg
Flash Point:23.333 °C
PSA：26.30000
Density:0.998 g/cm³
LogP:0.18270
Storage Temp.:2-8°C
Solubility.:Miscible with alcohol.
Water Solubility.:miscible
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:98.036779430
Heavy Atom Count:7
Complexity:107

Purity/Quality:

99% ^*data from raw suppliers

EthylPropargylate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,F
Hazard Codes:Xi,F
Statements: 10-36/37/38-36-11
Safety Statements: 26-36-37/39-16-33-29-24-23

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Other Classes -> Esters, Other
Canonical SMILES:CCOC(=O)C#C
Uses Halogenated derivatives were used as substrates for direct, asymmetric alkynylation of cyclic ?-ketoesters using chiral phase-transfer catalysts. Also employed in a one-pot , four-component synthesis of benzene-1,2,3,5-tetracarboxylates promoted by Ph3P. In organic synthesis; peptide coupling reagent. Ethyl propiolate is used as a precursor in the preparation of substituted anthraquinones and pyrazolo[1,5-a]pyridine, which exhibits anti-inflammatory activity. Further, it is employed in the synthesis of benzene-1,2,3,5-tetracarboxylates promoted by triphenylphosphine. Its halogenated derivatives are used as a substrate for direct, asymmetric alkynylation of cyclic beta-ketoesters using chiral phase-transfer catalysts.

Technology Process of Ethyl propiolate

There total 13 articles about Ethyl propiolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.7%