(R)-(-)-N-(2-Pyridyl)-1-(3,3-dimethylpiperidino)-2-aminopropan [German]

Base Information

Chemical Name:(R)-(-)-N-(2-Pyridyl)-1-(3,3-dimethylpiperidino)-2-aminopropan [German]
CAS No.:82189-97-7
Molecular Formula:C18H29N3O
Molecular Weight:303.4424
Hs Code.:
Nikkaji Number:J87.439F

Synonyms:(R)-(-)-N-(2-Pyridyl)-1-(3,3-dimethylpiperidino)-2-aminopropan [German];Propionamide, N-(2-(3,3-dimethylpiperidino)-1-methylethyl)-N-2-pyridyl-, R(-)-;R(-)-N-(2-(3,3-Dimethylpiperidino)-1-methylethyl)-N-2-pyridylpropionamide;(R)-(-)-N-(2-Pyridyl)-1-(3,3-dimethylpiperidino)-2-aminopropan;82189-97-7;24608-96-6;LS-124197;N-[[R,(?)]-2-(3,3-Dimethylpiperidino)-1-methylethyl]-N-(2-pyridyl)propionamide

Suppliers and Price of (R)-(-)-N-(2-Pyridyl)-1-(3,3-dimethylpiperidino)-2-aminopropan [German]

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-(-)-N-(2-Pyridyl)-1-(3,3-dimethylpiperidino)-2-aminopropan [German]

Chemical Property:

Vapor Pressure:2.92E-07mmHg at 25°C
Boiling Point:420°C at 760 mmHg
Flash Point:207.8°C
Density:1.024g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:303.231062557
Heavy Atom Count:22
Complexity:369

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(=O)N(C1=CC=CC=N1)C(C)CN2CCCC(C2)(C)C
Isomeric SMILES:CCC(=O)N(C1=CC=CC=N1)[C@H](C)CN2CCCC(C2)(C)C

Technology Process of (R)-(-)-N-(2-Pyridyl)-1-(3,3-dimethylpiperidino)-2-aminopropan [German]

There total 3 articles about (R)-(-)-N-(2-Pyridyl)-1-(3,3-dimethylpiperidino)-2-aminopropan [German] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 54151-28-9
N-(2-pyridyl)-1-(3,3-dimethylpiperidino)-2-aminopropan

: 82189-97-7,24639-20-1
(R)-(-)-N-propionyl-N-(2-pyridyl)-1-(3,3-dimethyl-piperidino)-2-aminopropan

Guidance literature:: Multi-step reaction with 3 steps

1: 49.1 g / tetrahydrofuran / 1.) 20 deg C, 1 h; 2.) 40 deg C, 10 h

2: 27.4 g / cc. hydrochloric acid / 10 h / Heating

3: 11.1 g / tetrahydrofuran / 1.) 20 deg C, 1 h; 2.) 40 deg C, 10 h

With hydrogenchloride; In tetrahydrofuran;

Reference yield:

: 82504-97-0
(R)-(-)-N-(2-Phenoxybutyryl)-N-(2-pyridyl)-1-(3,3-dimethyl-piperidino)-2-aminopropan

: 82189-97-7,24639-20-1
(R)-(-)-N-propionyl-N-(2-pyridyl)-1-(3,3-dimethyl-piperidino)-2-aminopropan

Guidance literature:: Multi-step reaction with 2 steps

1: 27.4 g / cc. hydrochloric acid / 10 h / Heating

2: 11.1 g / tetrahydrofuran / 1.) 20 deg C, 1 h; 2.) 40 deg C, 10 h

With hydrogenchloride; In tetrahydrofuran;