tert-butyl (4-{(E)-2-[6-(dimethylamino)pyridin-3-yl]vinyl}phenyl)methylcarbamate

Base Information

• Chemical Name: tert-butyl (4-{(E)-2-[6-(dimethylamino)pyridin-3-yl]vinyl}phenyl)methylcarbamate
• CAS No.: 1349698-33-4
• Molecular Formula: C₂₁H₂₇N₃O₂
• Molecular Weight: 353.464
• Mol file: 1349698-33-4.mol

Synonyms:tert-butyl (4-{(E)-2-[6-(dimethylamino)pyridin-3-yl]vinyl}phenyl)methylcarbamate

Chemical Property of tert-butyl (4-{(E)-2-[6-(dimethylamino)pyridin-3-yl]vinyl}phenyl)methylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of tert-butyl (4-{(E)-2-[6-(dimethylamino)pyridin-3-yl]vinyl}phenyl)methylcarbamate

There total 1 articles about tert-butyl (4-{(E)-2-[6-(dimethylamino)pyridin-3-yl]vinyl}phenyl)methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl (4-((diethoxyphosphoryl)methyl)phenyl)(methyl)carbamate (1349698-20-9) + 6-(dimethylamino)nicotine-3-carboxaldehyde (149805-92-5) → tert-butyl (4-{(E)-2-[6-(dimethylamino)pyridin-3-yl]vinyl}phenyl)methylcarbamate (1349698-33-4)

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; for 6h;

Reference yield:

tert-butyl (4-{(E)-2-[6-(dimethylamino)pyridin-3-yl]vinyl}phenyl)methylcarbamate (1349698-33-4) + ammonium acetate (631-61-8,92206-38-7) + acetic acid (64-19-7,77671-22-8) + methyl trifluoromethanesulfonate (333-27-7) → 5-[(E)-2-{4-[(tert-butoxycarbonyl)(methyl)amino]phenyl}vinyl]-N,N,N-trimethylpyridin-2-aminium acetate (1349698-32-3)

Guidance literature:

tert-butyl (4-{(E)-2-[6-(dimethylamino)pyridin-3-yl]vinyl}phenyl)methylcarbamate; methyl trifluoromethanesulfonate; In toluene; for 20h;

ammonium acetate; acetic acid; In hexane; pH=5.8;

upstream raw materials:

tert-butyl (4-((diethoxyphosphoryl)methyl)phenyl)(methyl)carbamate

6-(dimethylamino)nicotine-3-carboxaldehyde

Downstream raw materials:

5-[(E)-2-{4-[(tert-butoxycarbonyl)(methyl)amino]phenyl}vinyl]-N,N,N-trimethylpyridin-2-aminium acetate