4,8,11,15-tetrakis(p-tolylsulphonyl)-1-oxa-4,8,11,15-tetraazacycloheptadecane

Base Information

• Chemical Name: 4,8,11,15-tetrakis(p-tolylsulphonyl)-1-oxa-4,8,11,15-tetraazacycloheptadecane
• CAS No.: 120808-61-9
• Molecular Formula: C₄₀H₅₂N₄O₉S₄
• Molecular Weight: 861.138
• Mol file: 120808-61-9.mol

Synonyms:4,8,11,15-tetrakis(p-tolylsulphonyl)-1-oxa-4,8,11,15-tetraazacycloheptadecane

Chemical Property of 4,8,11,15-tetrakis(p-tolylsulphonyl)-1-oxa-4,8,11,15-tetraazacycloheptadecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,8,11,15-tetrakis(p-tolylsulphonyl)-1-oxa-4,8,11,15-tetraazacycloheptadecane

There total 3 articles about 4,8,11,15-tetrakis(p-tolylsulphonyl)-1-oxa-4,8,11,15-tetraazacycloheptadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1,1'-oxybis(2-bromo-ethane) (5414-19-7) + N,N',N'',N'''-tetratosyl-1,10-diamino-4,7-diazadecane (74676-47-4) → 4,8,11,15-tetrakis(p-tolylsulphonyl)-1-oxa-4,8,11,15-tetraazacycloheptadecane (120808-61-9)

Guidance literature:

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; In toluene; for 10h; Heating;

Reference yield:

N,N'-bis(3-aminopropyl)-1,2-diamine (10563-26-5) → 4,8,11,15-tetrakis(p-tolylsulphonyl)-1-oxa-4,8,11,15-tetraazacycloheptadecane (120808-61-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / sodium hydroxide / H₂O / 1.) 1 hr., 5 deg C, 2.) r.t., 3 hrs.

2: 94 percent / tetrabutylammonium iodide, sodium hydroxide (50 percent) / toluene; H₂O / 9 h / Heating

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; In water; toluene;

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → 4,8,11,15-tetrakis(p-tolylsulphonyl)-1-oxa-4,8,11,15-tetraazacycloheptadecane (120808-61-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / sodium hydroxide / H₂O / 1.) 1 hr., 5 deg C, 2.) r.t., 3 hrs.

2: 94 percent / tetrabutylammonium iodide, sodium hydroxide (50 percent) / toluene; H₂O / 9 h / Heating

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; In water; toluene;

upstream raw materials:

1,1'-oxybis(2-bromo-ethane)

N,N',N'',N'''-tetratosyl-1,10-diamino-4,7-diazadecane

N,N'-bis(3-aminopropyl)-1,2-diamine

p-toluenesulfonyl chloride