4-Nitrophenyl beta-D-glucopyranosiduronic acid

Base Information

Chemical Name:4-Nitrophenyl beta-D-glucopyranosiduronic acid
CAS No.:10344-94-2
Molecular Formula:C12H13NO9
Molecular Weight:315.237
Hs Code.:29329990
European Community (EC) Number:233-753-0
DSSTox Substance ID:DTXSID80209670
Nikkaji Number:J236.780G
Wikidata:Q27162353
ChEMBL ID:CHEMBL495244
Mol file:10344-94-2.mol

Synonyms:4-nitrophenylglucuronide;p-nitrophenyl-beta-D-glucuronide;p-nitrophenylglucuronide;para-nitrophenylglucuronide

Suppliers and Price of 4-Nitrophenyl beta-D-glucopyranosiduronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
p-Nitrophenyl b-D-Glucuronide
200mg
$ 389.00

TRC
4-Nitrophenylb-D-Glucuronide
100mg
$ 75.00

TCI Chemical
4-Nitrophenyl beta-D-Glucuronide [Substrate for beta-Glucuronidase] >98.0%(HPLC)
100mg
$ 63.00

Sigma-Aldrich
4-Nitrophenyl β-D-glucuronide ≥98% (TLC)
25mg
$ 31.40

Sigma-Aldrich
4-Nitrophenyl β-D-glucuronide ≥98% (TLC)
50mg
$ 54.00

Sigma-Aldrich
4-Nitrophenyl β-D-glucuronide ≥99.0% (TLC)
250mg
$ 218.00

Sigma-Aldrich
4-Nitrophenyl β-D-glucuronide Chromogenic substrate for β-glucuronidase (Km = ~0.22 mM).
1gm
$ 181.00

Sigma-Aldrich
p-Nitrophenyl-β-D-glucuronide - CAS 10344-94-2 - Calbiochem Chromogenic substrate for β-glucuronidase (Km = ~0.22 mM).
1 g
$ 173.90

Sigma-Aldrich
4-Nitrophenyl β-D-glucuronide ≥98% (TLC)
250mg
$ 173.00

Sigma-Aldrich
4-Nitrophenyl β-D-glucuronide ≥98% (TLC)
100mg
$ 94.60

Total 61 raw suppliers

Chemical Property of 4-Nitrophenyl beta-D-glucopyranosiduronic acid

Chemical Property:

Appearance/Colour:Crystalline solid
Melting Point:93 °C
Boiling Point:644.434 °C at 760 mmHg
PKA:2.69±0.70(Predicted)
Flash Point:343.541 °C
PSA：162.27000
Density:1.732 g/cm³
LogP:-0.61100
Storage Temp.:−20°C
Solubility.:H2O: 0.1 g/mL, clear, faintly yellow
XLogP3:-0.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:3
Exact Mass:315.05903099
Heavy Atom Count:22
Complexity:417

Purity/Quality:

98.0%min ^*data from raw suppliers

p-Nitrophenyl b-D-Glucuronide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1[N+](=O)[O-])OC2C(C(C(C(O2)C(=O)O)O)O)O
Isomeric SMILES:C1=CC(=CC=C1[N+](=O)[O-])O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)O)O)O)O
Uses 4-Nitrophenyl β-D-glucuronide has been used for determining the β-glucuronidase activity in urine samples, β-glucuronidase activity of bacteria in caecum content digesta and bovine liver. It has also been used to study the inhibitory effect of Phyllanthus amarus extracts on β-glucuronidase. 4-Nitrophenyl β-D-glucuronide has been used as substrate in acetate buffer to measure β-glucuronidase.

Technology Process of 4-Nitrophenyl beta-D-glucopyranosiduronic acid

There total 13 articles about 4-Nitrophenyl beta-D-glucopyranosiduronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 18472-49-6
methyl <4'-nitrophenyl 2,3,4-tri-O-acetyl-β-D-glucopyranosid>uronate

: 10344-94-2,60833-84-3
p-nitrophenyl-β-D-glucuronide

Guidance literature:: With methanol; lithium hydroxide; at 20 ℃; for 4h; Inert atmosphere;

Reference yield: 63.0%

: 2492-87-7
4-nitrophenyl-β-D-glucoside

: 10344-94-2,60833-84-3
p-nitrophenyl-β-D-glucuronide

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; trichloroisocyanuric acid; sodium hydrogencarbonate; potassium bromide; In water; acetone; at 0 - 45 ℃;
DOI:10.1246/bcsj.20100094

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 2616-64-0
UDP-glucuronic acid

: 10344-94-2,60833-84-3
p-nitrophenyl-β-D-glucuronide

Guidance literature:: With rat liver microsome solution; magnesium chloride; In various solvent(s); at 37 ℃; for 0.25h; pH=7.4;
DOI:10.1021/ac060970q