methyl 5-deoxy-2,3-di-O-(phenylmethyl)-D-ribofuranoside

Base Information

Chemical Name:methyl 5-deoxy-2,3-di-O-(phenylmethyl)-D-ribofuranoside
CAS No.:186456-58-6
Molecular Formula:C₂₀H₂₄O₄
Molecular Weight:328.408
Hs Code.:

Synonyms:methyl 5-deoxy-2,3-di-O-(phenylmethyl)-D-ribofuranoside

Suppliers and Price of methyl 5-deoxy-2,3-di-O-(phenylmethyl)-D-ribofuranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of methyl 5-deoxy-2,3-di-O-(phenylmethyl)-D-ribofuranoside

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of methyl 5-deoxy-2,3-di-O-(phenylmethyl)-D-ribofuranoside

There total 1 articles about methyl 5-deoxy-2,3-di-O-(phenylmethyl)-D-ribofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 186456-58-6
methyl 5-deoxy-2,3-di-O-(phenylmethyl)-D-ribofuranoside

: 64363-77-5
methyl 2,3,5-tri-O-benzyl-D-ribofuranoside

Guidance literature:

Reference yield: 92.0%

: 186456-58-6
methyl 5-deoxy-2,3-di-O-(phenylmethyl)-D-ribofuranoside

: 109-80-8
1.3-propanedithiol

: 186456-57-5
1,2-dibenzyloxy-1-([1,3]dithian-2-yl)-D-ribo-butane

Guidance literature:: With boron trifluoride diethyl etherate; In dichloromethane; at -48 - 20 ℃; for 2.5h;
DOI:10.1021/jm0503650

Reference yield:

: 186456-58-6
methyl 5-deoxy-2,3-di-O-(phenylmethyl)-D-ribofuranoside

: 4-N-phenylamino-5-phenyl-7-(5-deoxy-4-C-methyl-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 9 steps

1: 92 percent / BF₃*Et₂O / CH₂Cl₂ / 2.5 h / -48 - 20 °C

2: 80 percent / DMSO; oxalyl chloride; Et₃N / CH₂Cl₂ / -78 - -40 °C

3: 98 percent / tetrahydrofuran / 0.33 h / -78 °C

4: 88 percent / CaCO₃; MeI; H₂O / acetonitrile; tetrahydrofuran / Heating

5: H₂ / Pd(OH)2/C / ethyl acetate / 3 h / 20 °C / 760 Torr

6: 507 mg / p-TsOH*H₂O / dimethylformamide / 16 h / 20 °C

7: hexamethylphosphorus triamide; CCl₄ / toluene / 1.5 h / -78 - 0 °C

8: 223 mg / KOH; tris[2-(3-methoxyethoxy)ethyl]amine / toluene / 2 h / 20 °C

9: 65 percent / aq. TFA / 2 h / 0 - 20 °C

With tetrachloromethane; N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hydroxide; oxalyl dichloride; tris[2-(3-methoxyethoxy)ethyl]amine; boron trifluoride diethyl etherate; water; hydrogen; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; trifluoroacetic acid; calcium carbonate; methyl iodide; palladium dihydroxide; In tetrahydrofuran; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene; acetonitrile; 2: Swern oxidation;
DOI:10.1021/jm0503650