(E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)-N-methylacrylamido)piperidine-1,4-dicarboxylate

Base Information

Chemical Name:(E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)-N-methylacrylamido)piperidine-1,4-dicarboxylate
CAS No.:1059175-64-2
Molecular Formula:C₂₂H₂₈BrFN₂O₅
Molecular Weight:499.377
Hs Code.:

Synonyms:(E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)-N-methylacrylamido)piperidine-1,4-dicarboxylate

Suppliers and Price of (E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)-N-methylacrylamido)piperidine-1,4-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)-N-methylacrylamido)piperidine-1,4-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)-N-methylacrylamido)piperidine-1,4-dicarboxylate

There total 1 articles about (E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)-N-methylacrylamido)piperidine-1,4-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 1059175-63-1
(E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)acrylamido)piperidine-1,4-dicarboxylate

: 74-88-4
methyl iodide

: 1059175-64-2
(E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)-N-methylacrylamido)piperidine-1,4-dicarboxylate

Guidance literature:: (E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)acrylamido)piperidine-1,4-dicarboxylate; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran; for 18h;

Reference yield:

: 1059175-64-2
(E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)-N-methylacrylamido)piperidine-1,4-dicarboxylate

: 1059175-65-3
(E)-4-(3-(3-bromo-4-fluorophenyl)-N-methylacrylamido)-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid

Guidance literature:: (E)-1-tert-butyl 4-methyl 4-(3-(3-bromo-4-fluorophenyl)-N-methylacrylamido)piperidine-1,4-dicarboxylate; With methanol; sodium hydroxide; water; for 4h; Heating / reflux;

With hydrogenchloride; water; In methanol; pH=4;