allyl 2-(triphenylphosphoranylideneamino)aminobenzoic carboxamide

Base Information

• Chemical Name: allyl 2-(triphenylphosphoranylideneamino)aminobenzoic carboxamide
• CAS No.: 215734-48-8
• Molecular Formula: C₂₈H₂₅N₂OP
• Molecular Weight: 436.493
• Mol file: 215734-48-8.mol

Synonyms:allyl 2-(triphenylphosphoranylideneamino)aminobenzoic carboxamide

Chemical Property of allyl 2-(triphenylphosphoranylideneamino)aminobenzoic carboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of allyl 2-(triphenylphosphoranylideneamino)aminobenzoic carboxamide

There total 2 articles about allyl 2-(triphenylphosphoranylideneamino)aminobenzoic carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

N-allyl-2-aminobenzamide (4943-82-2) + triphenylphosphine (603-35-0) → allyl 2-(triphenylphosphoranylideneamino)aminobenzoic carboxamide (215734-48-8)

Guidance literature:

With triethylamine; In benzene; for 2h; Heating;

DOI:10.1055/s-1998-2170

Reference yield:

anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) → allyl 2-(triphenylphosphoranylideneamino)aminobenzoic carboxamide (215734-48-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / diethylphosphoryl cyanide, Et₃N / 1,2-dimethoxy-ethane / 1.) 0 deg C, 1 h, 2.) 40 deg C, 1 h

2: 77 percent / Et₃N / benzene; various solvent(s) / 2 h / Heating

With diethylphosphoryl cyanide; triethylamine; In 1,2-dimethoxyethane; benzene;

DOI:10.1055/s-1998-2170

Reference yield: 54.0%

benzoyl chloride (98-88-4) + allyl 2-(triphenylphosphoranylideneamino)aminobenzoic carboxamide (215734-48-8) → 3-allyl-2-phenylquinazolin-4(3H)-one (26060-01-5)

Guidance literature:

With triethylamine; In toluene; for 2h; Heating;

DOI:10.1055/s-1998-2170

upstream raw materials:

N-allyl-2-aminobenzamide

triphenylphosphine

anthranilic acid

Downstream raw materials:

3-allyl-2-phenylquinazolin-4(3H)-one