4-amino-1-[2-(2'-deoxy-3'-O-methoxymethyl-5'-trityl-β-D-ribofuranosyl)ethyl]-2-(2-octylthioethyl)-6-oxopyrimidine

Base Information

Chemical Name:4-amino-1-[2-(2'-deoxy-3'-O-methoxymethyl-5'-trityl-β-D-ribofuranosyl)ethyl]-2-(2-octylthioethyl)-6-oxopyrimidine
CAS No.:1200443-98-6
Molecular Formula:C₄₂H₅₅N₃O₅S
Molecular Weight:713.982
Hs Code.:

Synonyms:4-amino-1-[2-(2'-deoxy-3'-O-methoxymethyl-5'-trityl-β-D-ribofuranosyl)ethyl]-2-(2-octylthioethyl)-6-oxopyrimidine

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Chemical Property of 4-amino-1-[2-(2'-deoxy-3'-O-methoxymethyl-5'-trityl-β-D-ribofuranosyl)ethyl]-2-(2-octylthioethyl)-6-oxopyrimidine

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Technology Process of 4-amino-1-[2-(2'-deoxy-3'-O-methoxymethyl-5'-trityl-β-D-ribofuranosyl)ethyl]-2-(2-octylthioethyl)-6-oxopyrimidine

There total 1 articles about 4-amino-1-[2-(2'-deoxy-3'-O-methoxymethyl-5'-trityl-β-D-ribofuranosyl)ethyl]-2-(2-octylthioethyl)-6-oxopyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 1200443-97-5
4-amino-2-(2-octylthioethyl)-6-oxopyrimidine

: 428453-96-7
Toluene-4-sulfonic acid 2-((2S,4S,5R)-4-methoxymethoxy-5-trityloxymethyl-tetrahydro-furan-2-yl)-ethyl ester

: 1207271-76-8
C₄₂H₅₅N₃O₅S

: 1200443-98-6
4-amino-1-[2-(2'-deoxy-3'-O-methoxymethyl-5'-trityl-β-D-ribofuranosyl)ethyl]-2-(2-octylthioethyl)-6-oxopyrimidine

Guidance literature:: 4-amino-2-(2-octylthioethyl)-6-oxopyrimidine; With lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene; toluene; at 20 ℃; for 1h; Inert atmosphere;

Toluene-4-sulfonic acid 2-((2S,4S,5R)-4-methoxymethoxy-5-trityloxymethyl-tetrahydro-furan-2-yl)-ethyl ester; In tetrahydrofuran; n-heptane; ethylbenzene; toluene; at 100 ℃; Inert atmosphere;
DOI:10.1039/b915381k