1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone

Base Information

• Chemical Name: 1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone
• CAS No.: 120401-99-2
• Molecular Formula: C₂₀H₂₂O₄
• Molecular Weight: 326.392

Synonyms:1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone

Chemical Property of 1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone

There total 2 articles about 1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3,4-dihydro-2H-pyran (110-87-2) + 2-(4-hydroxyphenyl)-4-methoxyacetophenone (13619-63-1) → 1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone (120401-99-2)

Guidance literature:

With toluene-4-sulfonic acid; for 6h; Ambient temperature;

DOI:10.1248/cpb.36.3142

Reference yield:

1,4-di(4-methoxyphenyl)ethanone (120-44-5) → 1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone (120401-99-2)

Guidance literature:

Multi-step reaction with 2 steps

1: BBr₃ / CH₂Cl₂ / 3 h / -10 °C

2: p-TSA / benzene / 2.5 h / Ambient temperature

With boron tribromide; toluene-4-sulfonic acid; In dichloromethane; benzene;

DOI:10.1021/jm00034a009

Reference yield: 94.0%

1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone (120401-99-2) → 1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanol (155142-79-3)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 1h; Ambient temperature;

DOI:10.1021/jm00034a009

upstream raw materials:

3,4-dihydro-2H-pyran

2-(4-hydroxyphenyl)-4-methoxyacetophenone

1,4-di(4-methoxyphenyl)ethanone

Downstream raw materials:

4-methoxyphenyl 4-(2-tetrahydropyranyl)benzyl ketoxime

1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanol

3-[2-(4-Hydroxy-phenyl)-1-(4-methoxy-phenyl)-ethylsulfanyl]-propionic acid

methyl-6-(4'-hydroxyphenyl)-5-(4'-methoxyphenyl)-4-thiahexanoate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 120401-99-2 1-(4'-methoxyphenyl)-2-<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone

Send

Send

Metric Ton KG G Pound L ML

Send

Send