3,4-DICHLOROBENZAMIDE

Base Information

• Chemical Name: 3,4-DICHLOROBENZAMIDE
• CAS No.: 2670-38-4
• Molecular Formula: C7H5Cl2NO
• Molecular Weight: 190.029
• Hs Code.: 2924297099
• Mol file: 2670-38-4.mol

Synonyms:NSC 23779;3,4-Dichlorobenzamide;

Chemical Property of 3,4-DICHLOROBENZAMIDE

Chemical Property:

• Vapor Pressure: 0.00361mmHg at 25°C
• Melting Point: 140 °C
• Refractive Index: 1.596
• Boiling Point: 281.2 °C at 760 mmHg
• PKA: 15.12±0.50(Predicted)
• Flash Point: 123.9 °C
• PSA: 43.09000
• Density: 1.439 g/cm³
• LogP: 2.79260
• Solubility.: soluble in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,4-Dichlorobenzamide ^*data from reagent suppliers

Safty Information:

• Safety Statements: S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-DICHLOROBENZAMIDE

There total 11 articles about 3,4-DICHLOROBENZAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3,4-dichlorobenzaldehyde oxime (5331-92-0) → 3,4-dichlorobenzamide (2670-38-4)

Guidance literature:

With Cu(II) on nano silica functionalized triazine dendrimer; In water; at 20 ℃; for 0.75h; Green chemistry;

DOI:10.1002/jccs.202000469

Reference yield: 94.0%

3',4'-dichloroacetophenone (2642-63-9) → 3,4-dichlorobenzamide (2670-38-4)

Guidance literature:

With ammonia; iodine; In water; at 60 ℃; for 1h;

DOI:10.1021/ol901250c

Reference yield: 88.0%

3,4-dichlorobenzaldehyde (6287-38-3) → 3,4-dichlorobenzamide (2670-38-4)

Guidance literature:

With iron(III) chloride; hydroxylamine hydrochloride; caesium carbonate; In water; at 100 ℃; for 26h; chemoselective reaction;

DOI:10.1002/ejoc.201001738

upstream raw materials:

3,4-dichlorobenzoyl chloride

3,4-dichloro-benzonitrile

3',4'-dichloroacetophenone

4-bromo-1,2-dichlorobenzene

Downstream raw materials:

3,4-dichloro-benzoic acid-[bis-(2-cyano-ethyl)-amide]

3,4-dichloro-benzonitrile

ethyl 3,4-dichlorobenzimidate

N-benzyl-3,4-dichlorobenzamide

Refernces

• 1、 -. "Efficient nitriding reagent and application thereof". Paragraph 0333-0336. . Retrieved 2021/03/31.
• 2、 Solaiman Hamed, Ahmed,Mohammad Ali, Ehab. "Cu(II)–metformin immobilized on graphene oxide: an efficient and recyclable catalyst for the Beckmann rearrangement". . p. 701 - 714. Retrieved 2019/11/03.