wyosine

Base Information

• Chemical Name: wyosine
• CAS No.: 52662-10-9
• Molecular Formula: C14H17 N5 O5
• Molecular Weight: 335.319
• Mol file: 52662-10-9.mol

Synonyms:3-b-D-Ribofuranosylwye; Wyosine

Chemical Property of wyosine

Chemical Property:

• Vapor Pressure: 5.13E-29mmHg at 25°C
• Boiling Point: 827.6°C at 760 mmHg
• PKA: 13.20±0.70(Predicted)
• Flash Point: 454.3°C
• PSA: 127.04000
• Density: 1.86g/cm³
• LogP: -1.69740

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of wyosine

There total 7 articles about wyosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3,4-Dihydro-4,6-dimethyl-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-imidazo<1,2-a>purin-9-one (68768-34-3) → 3,4-Dihydro-4,6-dimethyl-3-β-D-ribofuranosyl-9H-imidazo<1,2-a>purin-9-one (52662-10-9)

Guidance literature:

With ammonia; at 20 ℃;

DOI:10.1016/S0040-4039(00)95491-1

Reference yield: 52.0%

2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-3-methyl-3,9-dihydro-purin-6-one; hydrate + 1-bromoacetone (598-31-2) → 3,4-Dihydro-4,6-dimethyl-3-β-D-ribofuranosyl-9H-imidazo<1,2-a>purin-9-one (52662-10-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 30 ℃; for 7h;

Reference yield: 52.0%

3-methylguanosine (68768-32-1) + 1-bromoacetone (598-31-2) → 3,4-Dihydro-4,6-dimethyl-3-β-D-ribofuranosyl-9H-imidazo<1,2-a>purin-9-one (52662-10-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 30 ℃;

DOI:10.1039/c39800001158

upstream raw materials:

3,4-Dihydro-4,6-dimethyl-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-imidazo<1,2-a>purin-9-one

N,N-dimethyl-formamide

1-bromoacetone

3-methylguanosine

Downstream raw materials:

3,4-Dihydro-4,6-dimethyl-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-imidazo<1,2-a>purin-9-one

3-methylguanine

7-methyl-3-β-D-ribofuranosylwye

7-methylwye

Refernces

• 1、 Itaya, Taisuke,Matsumoto, Hiroo,Watanabe, Tomoko,Harada, Tsunehiro. "Synthesis of 3-β-D-Ribofuranosylwye, the Most Probable Structure for Wyosine from Torulopsis utilis Phenylalanine Transfer Ribonucleic Acid". . p. 2339 - 2347. Retrieved 2007/10/02.