Technology Process of (2,6-bis{[(R)-1-methoxypropan-2-yl]oxy}phenyl)(2-methoxy-2-phenylethyl)selane
There total 2 articles about (2,6-bis{[(R)-1-methoxypropan-2-yl]oxy}phenyl)(2-methoxy-2-phenylethyl)selane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2,6-bis{[(R)-1-methoxypropan-2-yl]oxy}phenyl diselenide;
With
bromine;
In
tetrachloromethane; dichloromethane;
at -78 ℃;
for 0.333333h;
Inert atmosphere;
methanol;
With
silver trifluoromethanesulfonate;
In
tetrachloromethane; dichloromethane;
at -78 ℃;
for 0.5h;
Inert atmosphere;
styrene;
In
tetrachloromethane; dichloromethane;
at -78 ℃;
for 2h;
optical yield given as %de;
stereoselective reaction;
Inert atmosphere;
DOI:10.1002/ejoc.201001272
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: bromine / tetrachloromethane; dichloromethane / 0.33 h / -78 °C / Inert atmosphere
2.2: 0.5 h / -78 °C / Inert atmosphere
2.3: 2 h / -78 °C / Inert atmosphere
With
n-butyllithium; bromine;
In
tetrahydrofuran; tetrachloromethane; hexane; dichloromethane;
DOI:10.1002/ejoc.201001272
