2-benzylidene,3-benzyl-butanedioic anhydride

Base Information

• Chemical Name: 2-benzylidene,3-benzyl-butanedioic anhydride
• CAS No.: 18654-32-5
• Molecular Formula: C₁₈H₁₄O₃
• Molecular Weight: 278.307
• Mol file: 18654-32-5.mol

Synonyms:2-benzylidene,3-benzyl-butanedioic anhydride

Chemical Property of 2-benzylidene,3-benzyl-butanedioic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-benzylidene,3-benzyl-butanedioic anhydride

There total 4 articles about 2-benzylidene,3-benzyl-butanedioic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

(3E, 4E)-3,4-dibenzylidenedihydrofuran-2,5-dione (16269-23-1,53243-99-5,53244-00-1,53244-01-2) → 2,3-dibenzylbut-2-en-dioic anhydride (71481-05-5) + 2-benzylidene,3-benzyl-butanedioic anhydride (18654-32-5) + 2,3-dibenzylbutanedioic anhydride (101723-61-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; at 20 ℃; for 20h; under 760 Torr;

DOI:10.1016/j.tet.2004.04.060

Reference yield:

E,E-2,3-dibenzylidene succinic acid (53243-89-3) → 2-benzylidene,3-benzyl-butanedioic anhydride (18654-32-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / acetyl chloride / 2 h / Heating

2: 27 percent / H₂ / Pd/C / ethyl acetate / 20 h / 20 °C / 760 Torr

With hydrogen; acetyl chloride; palladium on activated charcoal; In ethyl acetate;

DOI:10.1016/j.tet.2004.04.060

Reference yield:

benzaldehyde (100-52-7) → 2-benzylidene,3-benzyl-butanedioic anhydride (18654-32-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 19 percent / Na / diethyl ether / 12 h / 0 - 20 °C

2: 84 percent / acetyl chloride / 2 h / Heating

3: 27 percent / H₂ / Pd/C / ethyl acetate / 20 h / 20 °C / 760 Torr

With hydrogen; sodium; acetyl chloride; palladium on activated charcoal; In diethyl ether; ethyl acetate;

DOI:10.1016/j.tet.2004.04.060

upstream raw materials:

(3E, 4E)-3,4-dibenzylidenedihydrofuran-2,5-dione

E,E-2,3-dibenzylidene succinic acid

benzaldehyde