(1R_P,3S,3aR)-2-{2-[(1S_P,3R,3aS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide

Base Information

• Chemical Name: (1R_P,3S,3aR)-2-{2-[(1S_P,3R,3aS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide
• CAS No.: 940295-95-4
• Molecular Formula: C₄₀H₃₈N₂O₂P₂
• Molecular Weight: 640.701

Synonyms:(1R_P,3S,3aR)-2-{2-[(1S_P,3R,3aS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide

Chemical Property of (1R_P,3S,3aR)-2-{2-[(1S_P,3R,3aS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R_P,3S,3aR)-2-{2-[(1S_P,3R,3aS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide

There total 2 articles about (1R_P,3S,3aR)-2-{2-[(1S_P,3R,3aS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

N,N'-ethane-1,2-diylbis[N-benzyl-P,P-diphenyl(phosphinic amide)] (940295-88-5) → (1RP,3S,3aR)-2-{2-[(1SP,3R,3aS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide (940295-95-4) + (1RSP,3SR,3aRS)-2-{2-[(1RSP,3SR,3aRS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide + N-{2-[(1RSP,3RS,3aSR,7aSR)-1,3-diphenyl-1-oxo-1,3,3a,7a-tetrahydro-2H-2,1-benzazaphosphol-2-yl]ethyl}-N-benzyl-P,P-diphenylphosphinic amide + N-{2-[(1RSP,3SR,3aRS)-1,3-diphenyl-1-oxo-1,3,3a,6-tetrahydro-2H-2,1-benzazaphosphol-2-yl]ethyl}-N-benzyl-P,P-diphenylphosphinic amide

Guidance literature:

N,N'-ethane-1,2-diylbis[N-benzyl-P,P-diphenyl(phosphinic amide)]; With N,N,N,N,N,N-hexamethylphosphoric triamide; sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -90 ℃; for 1h;

With 2,6-di-tert-butyl-4-methyl-phenol; In tetrahydrofuran; cyclohexane; at -90 ℃; for 0.5h; Further stages.;

DOI:10.1021/jo070276q

Reference yield: 35.0%

N,N'-ethane-1,2-diylbis[N-benzyl-P,P-diphenyl(phosphinic amide)] (940295-88-5) → (1RP,3R,3aS,7aS)-2-{2-[(1SP,3S,3aR,7aR)-1,3-diphenyl-1-oxide-2,3,3a,7a-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,7a-tetrahydro-1H-2,1-benzazaphosphol 1-oxide + (1RSP,3RS,3aSR,7aSR)-2,2'-ethane-1,2-diylbis(1,3-diphenyl-2,3,3a,7a-tetrahydro-1H-2,1-benzazaphosphol) 1,1'-dioxide + (1RP,3S,3aR)-2-{2-[(1SP,3R,3aS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide (940295-95-4) + (1RSP,3SR,3aRS)-2-{2-[(1RSP,3SR,3aRS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide

Guidance literature:

N,N'-ethane-1,2-diylbis[N-benzyl-P,P-diphenyl(phosphinic amide)]; With N,N,N,N,N,N-hexamethylphosphoric triamide; sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -90 ℃; for 0.5h;

With methanol; In tetrahydrofuran; cyclohexane; at -90 ℃; for 0.5h; Further stages. Further byproducts.;

DOI:10.1021/jo070276q

Reference yield: 97.0%

methanol (67-56-1) + (1RP,3S,3aR)-2-{2-[(1SP,3R,3aS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide (940295-95-4) → C42H46N2O4P2

Guidance literature:

With hydrogenchloride; In diethyl ether; at 20 ℃; for 0.833333h;

DOI:10.1021/jo070276q

upstream raw materials:

N,N'-ethane-1,2-diylbis[N-benzyl-P,P-diphenyl(phosphinic amide)]

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 940295-95-4 (1R_P,3S,3aR)-2-{2-[(1S_P,3R,3aS)-1,3-diphenyl-1-oxide-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol-2-yl]ethyl}-1,3-diphenyl-2,3,3a,6-tetrahydro-1H-2,1-benzazaphosphol 1-oxide

Send

Send

Metric Ton KG G Pound L ML

Send

Send