(1R,2S,1'R)-(-)-2-(1'-phenylethylamino)-1-phenyl-1-propanol hydrochloride

Base Information

Chemical Name:(1R,2S,1'R)-(-)-2-(1'-phenylethylamino)-1-phenyl-1-propanol hydrochloride
CAS No.:1161754-77-3
Molecular Formula:C₁₇H₂₁NO*ClH
Molecular Weight:291.821
Hs Code.:

Synonyms:(1R,2S,1'R)-(-)-2-(1'-phenylethylamino)-1-phenyl-1-propanol hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2S,1'R)-(-)-2-(1'-phenylethylamino)-1-phenyl-1-propanol hydrochloride

Chemical Property:

Purity/Quality:

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Technology Process of (1R,2S,1'R)-(-)-2-(1'-phenylethylamino)-1-phenyl-1-propanol hydrochloride

There total 7 articles about (1R,2S,1'R)-(-)-2-(1'-phenylethylamino)-1-phenyl-1-propanol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 154170-05-5
(1R,2S)-1-phenyl-2-[((1R)-phenylethyl)amino]-1-propanol

: 1161754-77-3
(1R,2S,1'R)-(-)-2-(1'-phenylethylamino)-1-phenyl-1-propanol hydrochloride

Guidance literature:: With hydrogenchloride;
DOI:10.1016/j.bmcl.2014.05.027

Reference yield:

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 1161754-77-3
(1R,2S,1'R)-(-)-2-(1'-phenylethylamino)-1-phenyl-1-propanol hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / toluene / 110 °C

2: palladium 10% on activated carbon; hydrogen / isopropyl alcohol / 0 - 10 °C / 2068.65 - 2585.81 Torr

3: hydrogenchloride

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; toluene-4-sulfonic acid; In isopropyl alcohol; toluene;
DOI:10.1016/j.bmcl.2014.05.027

Reference yield:

: 1798-60-3
(R)-1-hydroxy-1-phenyl-2-propanone

: 1161754-77-3
(1R,2S,1'R)-(-)-2-(1'-phenylethylamino)-1-phenyl-1-propanol hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / toluene / 110 °C

2: palladium 10% on activated carbon; hydrogen / isopropyl alcohol / 0 - 10 °C / 2068.65 - 2585.81 Torr

3: hydrogenchloride

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; toluene-4-sulfonic acid; In isopropyl alcohol; toluene;
DOI:10.1016/j.bmcl.2014.05.027