(S)-3-(1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-yloxy)benzyl isopropyl carbonate

Base Information

Chemical Name:(S)-3-(1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-yloxy)benzyl isopropyl carbonate
CAS No.:1184746-22-2
Molecular Formula:C₂₂H₂₆FNO₆S
Molecular Weight:451.516
Hs Code.:

Synonyms:(S)-3-(1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-yloxy)benzyl isopropyl carbonate

Suppliers and Price of (S)-3-(1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-yloxy)benzyl isopropyl carbonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (S)-3-(1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-yloxy)benzyl isopropyl carbonate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (S)-3-(1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-yloxy)benzyl isopropyl carbonate

There total 4 articles about (S)-3-(1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-yloxy)benzyl isopropyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1184746-23-3
C₁₈H₂₀FNO₄S

: 108-23-6
isopropyl chloroformate

: 1184746-22-2
(S)-3-(1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-yloxy)benzyl isopropyl carbonate

Guidance literature:: With potassium hexamethylsilazane; In tetrahydrofuran; toluene; at 20 ℃;

Reference yield:

: 1054521-30-0
(R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol

: 1184746-22-2
(S)-3-(1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-yloxy)benzyl isopropyl carbonate

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / dichloromethane

2: potassium carbonate / N,N-dimethyl-formamide / 80 °C

3: potassium hexamethylsilazane / tetrahydrofuran; toluene / 20 °C

With pyridine; potassium hexamethylsilazane; potassium carbonate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;

Reference yield:

: 1054521-32-2
(R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol methanesulfonate

: 1184746-22-2
(S)-3-(1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-yloxy)benzyl isopropyl carbonate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 80 °C

2: potassium hexamethylsilazane / tetrahydrofuran; toluene / 20 °C

With potassium hexamethylsilazane; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide; toluene;