1-(3-(Trimethoxysilyl)propyl)-1H-imidazole

Base Information

• Chemical Name: 1-(3-(Trimethoxysilyl)propyl)-1H-imidazole
• CAS No.: 70851-51-3
• Deprecated CAS: 1207539-06-7
• Molecular Formula: C9H18 N2 O3 Si
• Molecular Weight: 230.339
• European Community (EC) Number: 274-937-0
• DSSTox Substance ID: DTXSID7072175
• Nikkaji Number: J288.644H
• Wikidata: Q82000110
• Mol file: 70851-51-3.mol

Synonyms:70851-51-3;N-(Trimethoxysilylpropyl)imidazole;1-(3-(Trimethoxysilyl)propyl)-1H-imidazole;3-imidazol-1-ylpropyl(trimethoxy)silane;1H-Imidazole,1-[3-(trimethoxysilyl)propyl]-;1H-Imidazole, 1-[3-(trimethoxysilyl)propyl]-;EINECS 274-937-0;1H-Imidazole, 1-(3-(trimethoxysilyl)propyl)-;1-[3-(trimethoxysilyl)propyl]-1H-imidazole;C9H18N2O3Si;SCHEMBL406663;DTXSID7072175;C9-H18-N2-O3-Si;LLIFKTIQXYJAHL-UHFFFAOYSA-;N-(trimethoxysilylpropyl)-imidazole;[3-(1-Imidazolyl)propyl]trimethoxysilane;FT-0629328;F71641;A837008

Chemical Property of 1-(3-(Trimethoxysilyl)propyl)-1H-imidazole

Chemical Property:

• Vapor Pressure: 0.00361mmHg at 25°C
• Boiling Point: 290.4°C at 760 mmHg
• PKA: 7.07±0.10(Predicted)
• Flash Point: 129.4°C
• PSA: 45.51000
• Density: 1.04g/cm³
• LogP: 1.15130
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 230.10866897
• Heavy Atom Count: 15
• Complexity: 171

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(3-(trimethoxysilyl)propyl)-1H-imidazole 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CO[Si](CCCN1C=CN=C1)(OC)OC

Technology Process of 1-(3-(Trimethoxysilyl)propyl)-1H-imidazole

There total 5 articles about 1-(3-(Trimethoxysilyl)propyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1H-imidazole (288-32-4) + 3-Chloropropyltrimethoxysilan (2530-87-2) → 1-[3-(trimethoxysilyl)propyl]imidazole (70851-51-3)

Guidance literature:

1H-imidazole; With sodium methylate; In tetrahydrofuran; at 40 ℃; for 1.33333h; Large scale;

3-Chloropropyltrimethoxysilan; In tetrahydrofuran; at 60 - 90 ℃; for 6h; Solvent; Reagent/catalyst; Temperature; Large scale;

Reference yield: 89.0%

1H-imidazole (288-32-4) + 3-iodopropyltrimethoxysilane (14867-28-8) → 1-[3-(trimethoxysilyl)propyl]imidazole (70851-51-3)

Guidance literature:

1H-imidazole; With sodium hydride; In tetrahydrofuran; at 0 ℃; Inert atmosphere;

3-iodopropyltrimethoxysilane; In tetrahydrofuran; Inert atmosphere; Reflux;

DOI:10.1002/chem.201400392

Reference yield: 73.0%

imidazolyl sodium (5587-42-8) + 3-iodopropyltrimethoxysilane (14867-28-8) → 1-[3-(trimethoxysilyl)propyl]imidazole (70851-51-3)

Guidance literature:

In tetrahydrofuran; at 66 ℃; for 13h;

DOI:10.1055/s-2005-861784

upstream raw materials:

imidazolyl sodium

3-iodopropyltrimethoxysilane

1H-imidazole

3-Chloropropyltrimethoxysilan

Refernces

• 1、 Cazin, Catherine S. J.,Veith, Michael,Braunstein, Pierre,Bedford, Robin B.. "Versatile methods for the synthesis of Si(OR)3-functionalised imidazolium salts, potential precursors for heterogeneous NHC catalysts and composite materials". . p. 622 - 626. Retrieved 2005.
• 2、 Bigdeli, Akram,Karimi, Babak,Khodadadi Karimvand, Somaiyeh,Khorasani, Mojtaba,Safari, Ali Asghar,Vali, Hojatollah. "Aerobic oxidation of alcohols catalyzed by in situ generated gold nanoparticles inside the channels of periodic mesoporous organosilica with ionic liquid framework". supporting information. p. 70 - 79. Retrieved 2020/06/08.
• 3、 Luque, Rafael,Nafe, Mostafa,Rajabi, Fatemeh,Rezanejad Bardajee, Ghasem. "Tungstate ion (WO42-) confined in hydrophilic/hydrophobic nanomaterials functionalized br?nsted acidic ionic liquid as highly active catalyst in the selective aerobic oxidation of alcohols in water". . . Retrieved 2020/10/18.