Technology Process of C10H8O3
There total 4 articles about C10H8O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
ethyl 2-(2-ethynylphenoxy)acetate;
With
lithium hydroxide monohydrate;
In
tetrahydrofuran; water;
at 20 ℃;
for 12h;
Inert atmosphere;
With
hydrogenchloride;
In
water;
pH=4;
DOI:10.1021/jo300063u
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere
2.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 12 h / 20 °C / Inert atmosphere
2.2: pH 4
With
lithium hydroxide monohydrate; tetrabutyl ammonium fluoride;
In
tetrahydrofuran; water;
DOI:10.1021/jo300063u
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C / Inert atmosphere
2.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere
4.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 12 h / 20 °C / Inert atmosphere
4.2: pH 4
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; lithium hydroxide monohydrate; tetrabutyl ammonium fluoride; potassium carbonate; triethylamine;
In
tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1021/jo300063u
