tyrosinyl-5'-AMP

Base Information

Chemical Name:tyrosinyl-5'-AMP
CAS No.:6372-08-3
Molecular Formula:C₁₉H₂₅N₆O₈P
Molecular Weight:496.417
Hs Code.:
Mol file:6372-08-3.mol

Synonyms:5'-Adenylicacid, mono[2-amino-3-(4-hydroxyphenyl)propyl] ester, (S)-; 5'-Adenylic acid,mono[L-2-amino-3-(p-hydroxyphenyl)propyl] ester (8CI); 1-Propanol,2-amino-3-(p-hydroxyphenyl)-, 1-(hydrogen 5'-adenylate), L- (8CI); L-Tyrosinoladenylate

Suppliers and Price of tyrosinyl-5'-AMP

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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price

Total 3 raw suppliers

Chemical Property of tyrosinyl-5'-AMP

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of tyrosinyl-5'-AMP

There total 8 articles about tyrosinyl-5'-AMP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 256643-00-2
Phosphoric acid (S)-2-amino-3-(4-hydroxy-phenyl)-propyl ester (3aR,4R,6R,6aR)-6-(6-amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester

: 6372-08-3
Phosphoric acid (S)-2-amino-3-(4-hydroxy-phenyl)-propyl ester (2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester

Guidance literature:: With trifluoroacetic acid; at 20 ℃; for 4h;
DOI:10.1016/S0968-0896(99)00192-3

Reference yield:

: 39947-04-1
N-6-benzoyl-2',3'-O-isopropylideneadenosine

: 6372-08-3
Phosphoric acid (S)-2-amino-3-(4-hydroxy-phenyl)-propyl ester (2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: iPr₂NEt / CH₂Cl₂ / 0.25 h / 20 °C

2: 1H-tetrazole / acetonitrile / 0.25 h / 20 °C

3: 0.723 g / I₂; 2,6-lutidine / H₂O; tetrahydrofuran / 0.25 h

4: 81 percent / n-BuNH₂ / methanol / 24 h / 20 °C

5: 41 percent / H₂ / Pd/C / dioxane; H₂O; acetic acid

6: 89 percent / aq. TFA / 4 h / 20 °C

With 2,6-dimethylpyridine; 1H-tetrazole; hydrogen; iodine; N-butylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; acetic acid; acetonitrile; 1: Substitution / 2: Substitution / 3: Oxidation / 4: Hydrolysis / 5: Catalytic hydrogenation / 6: Ring cleavage;
DOI:10.1016/S0968-0896(99)00192-3

Reference yield:

: 155264-06-5
Diisopropyl-phosphoramidous acid (3aR,4R,6R,6aR)-6-(6-benzoylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester methyl ester

: 6372-08-3
Phosphoric acid (S)-2-amino-3-(4-hydroxy-phenyl)-propyl ester (2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 1H-tetrazole / acetonitrile / 0.25 h / 20 °C

2: 0.723 g / I₂; 2,6-lutidine / H₂O; tetrahydrofuran / 0.25 h

3: 81 percent / n-BuNH₂ / methanol / 24 h / 20 °C

4: 41 percent / H₂ / Pd/C / dioxane; H₂O; acetic acid

5: 89 percent / aq. TFA / 4 h / 20 °C

With 2,6-dimethylpyridine; 1H-tetrazole; hydrogen; iodine; N-butylamine; trifluoroacetic acid; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; methanol; water; acetic acid; acetonitrile; 1: Substitution / 2: Oxidation / 3: Hydrolysis / 4: Catalytic hydrogenation / 5: Ring cleavage;
DOI:10.1016/S0968-0896(99)00192-3