[(p-nitrophenylamino)-4-nitrophenylmethylidene]propanedinitrile

Base Information

• Chemical Name: [(p-nitrophenylamino)-4-nitrophenylmethylidene]propanedinitrile
• CAS No.: 439385-10-1
• Molecular Formula: C₁₆H₉N₅O₄
• Molecular Weight: 335.279
• Mol file: 439385-10-1.mol

Synonyms:[(p-nitrophenylamino)-4-nitrophenylmethylidene]propanedinitrile

Chemical Property of [(p-nitrophenylamino)-4-nitrophenylmethylidene]propanedinitrile

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of [(p-nitrophenylamino)-4-nitrophenylmethylidene]propanedinitrile

There total 2 articles about [(p-nitrophenylamino)-4-nitrophenylmethylidene]propanedinitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.1%

2-[chloro(4-nitrophenyl)methylene]malononitrile (57337-93-6) + 4-nitro-aniline (100-01-6,104810-17-5) → [(p-nitrophenylamino)-4-nitrophenylmethylidene]propanedinitrile (439385-10-1)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In 1-methyl-pyrrolidin-2-one; at 80 ℃; for 12h;

DOI:10.1021/ma0115085

Reference yield:

4-nitro-benzoyl chloride (122-04-3) → [(p-nitrophenylamino)-4-nitrophenylmethylidene]propanedinitrile (439385-10-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaOH / benzyltriethylammonium chloride / CH₂Cl₂; H₂O / 11 h / 0 - 20 °C

1.2: 8.20 g / POCl₃ / 1,2-dichloro-ethane / 12 h / Heating

2.1: 78.1 percent / 1,4-diazabicyclo[2.2.2]octane / 1-methyl-pyrrolidin-2-one / 12 h / 80 °C

With 1,4-diaza-bicyclo[2.2.2]octane; sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In 1-methyl-pyrrolidin-2-one; dichloromethane; water;

DOI:10.1021/ma0115085

Reference yield: 83.4%

[(p-nitrophenylamino)-4-nitrophenylmethylidene]propanedinitrile (439385-10-1) → [(p-aminophenylamino)-4-aminophenylmethylidene]propanedinitrile (439385-16-7)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; In ethanol; for 12h; Heating;

DOI:10.1021/ma0115085

upstream raw materials:

2-[chloro(4-nitrophenyl)methylene]malononitrile

4-nitro-aniline

4-nitro-benzoyl chloride

Downstream raw materials:

[(p-aminophenylamino)-4-aminophenylmethylidene]propanedinitrile