3''-N-acetyl-3,2',6'-tri-N-benzoylsisomicin

Base Information

• Chemical Name: 3''-N-acetyl-3,2',6'-tri-N-benzoylsisomicin
• CAS No.: 79249-23-3
• Molecular Formula: C₄₂H₅₁N₅O₁₁
• Molecular Weight: 801.894
• Mol file: 79249-23-3.mol

Synonyms:3''-N-acetyl-3,2',6'-tri-N-benzoylsisomicin

Chemical Property of 3''-N-acetyl-3,2',6'-tri-N-benzoylsisomicin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3''-N-acetyl-3,2',6'-tri-N-benzoylsisomicin

There total 1 articles about 3''-N-acetyl-3,2',6'-tri-N-benzoylsisomicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-Acetylimidazole (2466-76-4) + 3,2',6'-tri-N-benzoylsisomicin (79249-22-2) → 3''-N-acetyl-3,2',6'-tri-N-benzoylsisomicin (79249-23-3)

Guidance literature:

In tetrahydrofuran; water; at 25 ℃; for 16h;

DOI:10.1039/P19810002168

Reference yield: 85.0%

3''-N-acetyl-3,2',6'-tri-N-benzoylsisomicin (79249-23-3) → 3''-N-acetyl-3,2',6'-tri-N-benzoyl-1-deamino-1-oxosisomicin (79249-24-4)

Guidance literature:

With malonic acid; 3,5-di-tert-butyl-o-benzoquinone; In tetrahydrofuran; methanol; at 25 ℃; for 42h; pH = 4;

DOI:10.1039/P19810002168

Reference yield:

3''-N-acetyl-3,2',6'-tri-N-benzoylsisomicin (79249-23-3) → C42H50N4O12

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / 3,5-di-t-butyl-1,2-benzoquinone, aq. malonic acid / methanol; tetrahydrofuran / 42 h / 25 °C / pH = 4

2: L-selectride / tetrahydrofuran / 2 h / -78 °C

With malonic acid; 3,5-di-tert-butyl-o-benzoquinone; L-Selectride; In tetrahydrofuran; methanol;

DOI:10.1039/P19810002168

upstream raw materials:

N-Acetylimidazole

3,2',6'-tri-N-benzoylsisomicin

Downstream raw materials:

3''-N-acetyl-3,2',6'-tri-N-benzoyl-1-deamino-1-oxosisomicin

1-deamino-1-hydroxysisomicin

1-deamino-1-epi-hydroxysisomicin

1-epi-N-ethylsisomicin