5-benzyl 2-ethyl 4H,5H,6H,7H-[1,3]oxazolo[4,5-c]pyridine-2,5-dicarboxylate

Base Information

• Chemical Name: 5-benzyl 2-ethyl 4H,5H,6H,7H-[1,3]oxazolo[4,5-c]pyridine-2,5-dicarboxylate
• CAS No.: 1247883-69-7
• Molecular Formula: C₁₇H₁₈N₂O₅
• Molecular Weight: 330.34
• Mol file: 1247883-69-7.mol

Synonyms:6,7-dihydrooxazolo[4,5-c]pyridine-2,5-carboxykic acid 5-benzyl ester 2-ethyl ester

Chemical Property of 5-benzyl 2-ethyl 4H,5H,6H,7H-[1,3]oxazolo[4,5-c]pyridine-2,5-dicarboxylate

Chemical Property:

• Boiling Point: 488.7±55.0 °C(Predicted)
• PKA: -1.32±0.20(Predicted)
• Density: 1.290±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

2-Ethyl5-(Phenylmethyl)6,7-Dihydro-oxazolo[4,5-C]pyridine-2,5(4H)-dicarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-benzyl 2-ethyl 4H,5H,6H,7H-[1,3]oxazolo[4,5-c]pyridine-2,5-dicarboxylate

There total 1 articles about 5-benzyl 2-ethyl 4H,5H,6H,7H-[1,3]oxazolo[4,5-c]pyridine-2,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

3-ethoxalylamino-4-oxopiperidine-1-carboxylic acid benzyl ester → 6,7-dihydrooxazolo[4,5-c]pyridine-2,5-carboxykic acid 5-benzyl ester 2-ethyl ester (1247883-69-7)

Guidance literature:

3-ethoxalylamino-4-oxopiperidine-1-carboxylic acid benzyl ester; With trichlorophosphate; In 1,4-dioxane; at 100 ℃; for 4h;

With sodium carbonate; In water; pH=9;

Reference yield: 84.0%

6,7-dihydrooxazolo[4,5-c]pyridine-2,5-carboxykic acid 5-benzyl ester 2-ethyl ester (1247883-69-7) + 2,2-dimethoxyethylamine (22483-09-6) → 2-(2,2-dimethoxyethylcarbamoyl)-6,7-dihydro-4H-oxazolo[4,5-c]pyridine-5-carboxykic acid benzyl ester (1247883-70-0)

Guidance literature:

In methanol; at 20 ℃;

Downstream raw materials:

2-(2,2-dimethoxyethylcarbamoyl)-6,7-dihydro-4H-oxazolo[4,5-c]pyridine-5-carboxykic acid benzyl ester

Refernces