(S)-1-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-pyrrolidine-2-carboxylic acid tert-butylamide

Base Information

Chemical Name:(S)-1-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-pyrrolidine-2-carboxylic acid tert-butylamide
CAS No.:128053-39-4
Molecular Formula:C₁₉H₃₁N₃O₂
Molecular Weight:333.474
Hs Code.:

Synonyms:(S)-1-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-pyrrolidine-2-carboxylic acid tert-butylamide

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Chemical Property of (S)-1-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-pyrrolidine-2-carboxylic acid tert-butylamide

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Technology Process of (S)-1-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-pyrrolidine-2-carboxylic acid tert-butylamide

There total 7 articles about (S)-1-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-pyrrolidine-2-carboxylic acid tert-butylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 128018-20-2
N-<1-phenyl-2(S)-<(benzyloxycarbonyl)amino>-3(R)-hydroxybutan>-4-L-prolyl-tert-butyl amide

: 128053-39-4
(S)-1-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-pyrrolidine-2-carboxylic acid tert-butylamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate;
DOI:10.1021/ja982893p

Reference yield:

: 128018-44-0
N-benzyloxycarbonyl-3(S)-amino-1,2(S)epoxy-4-phenylbutane

: 128053-39-4
(S)-1-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-pyrrolidine-2-carboxylic acid tert-butylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / methanol / Heating

2: H₂ / Pd/C / ethanol / 1 h / 760 Torr

With hydrogen; palladium on activated charcoal; In methanol; ethanol;
DOI:10.1016/j.bmc.2006.01.031

Reference yield:

: 128018-18-8
L-proline tert-butylamide

: 128053-39-4
(S)-1-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-pyrrolidine-2-carboxylic acid tert-butylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / methanol / Heating

2: H₂ / Pd/C / ethanol / 1 h / 760 Torr

With hydrogen; palladium on activated charcoal; In methanol; ethanol;
DOI:10.1016/j.bmc.2006.01.031